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Abstract

In this chapter we will deal with tactile senses originating in mechanoreceptors of the skin. The skin is the largest organ in the body, accounting for about 16% of its weight [1] and, as an interface between the body’s inside and outside, exerts a number of functions, including sensation mediated by a variety of sensory organs. Touch is probably the phylogenetically oldest sense and, up to the most developed species, of immense significance for physical and psychic wellbeing. Newborns, in particular, suffer tremendously from deprivation of touch contact with other human beings, not only the mother. They are retarded in growth, physical and psychic development. During deprivation, their heart rate, body temperature, brainwave and sleep patterns and immune responses are changed [1]. Touch also plays a major role in sexual life and, hence, reproduction. Its importance in human life has been engrained in language in an enormous number of idioms and proverbs [1].

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References

  1. Ackerman D (1990) A natural history of the senses. Random House, New York

    Google Scholar 

  2. Alloway KD, Burton H (1991) Differential effects of GABA and bicuculline on rapidly- and slowly-adapting neurons in primary somatosensory cortex of primates. Exp Brain Res 85:598–610

    Article  PubMed  CAS  Google Scholar 

  3. Andersen RA, Snyder LH, Li C-S, Stricanne B (1993) Coordinate transformations in the representation of spatial information. Curr Opin Neurobiol 3:171–176

    Article  PubMed  CAS  Google Scholar 

  4. Brodal A (1981) Neurological anatomy. In relation to clinical medicine, 3rd edn. Oxford University Press, New York

    Google Scholar 

  5. Brown AG (1981) Organization of the spinal cord. The anatomy and physiology of identified neurones. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  6. Brown AG, Iggo A (1967) A quantitative study of cutaneous receptors and afferent fibres in the cat and rabbit. J Physiol (Lond) 193:707–733

    CAS  Google Scholar 

  7. Burgess PR, Mei J, Tuckett RP, Horch KW, Ballinger CM, Poulos DA (1983) The neural signal for skin indentation depth. I. Changing indentations. J Neurosci 8:1572–1585

    Google Scholar 

  8. Calford MD, Tweedale R (1991) Acute changes in cutaneous receptive fields in primary somatosensory cortex after digit denervation in adult flying fox. J Neurophysiol 65:178–187

    PubMed  CAS  Google Scholar 

  9. Caselli RJ (1991) Rediscovering tactile agnosia. Mayo Clin Proc 66:129–142

    Article  PubMed  CAS  Google Scholar 

  10. Cohen RH, Vierck CJ Jr (1993a) Population estimates for responses of cutaneous mechanoreceptors to a vertically indenting probe on the glabrous skin or monkeys. Exp Brain Res 94:105–119

    PubMed  CAS  Google Scholar 

  11. Cohen RH, Vierck CJ Jr (1993b) Relationships between touch sensations and estimated population responses of peripheral afferent mechanoreceptors. Exp Brain Res 94:120–130

    PubMed  CAS  Google Scholar 

  12. Darian-Smith I (1984) The sense of touch: performance and peripheral neural processes. In: Darian-Smith I (ed) The nervous system, vol III, sensory processes, part 2 (Handbook of physiology). American Physiological Society, Bethesda, pp 739–788

    Google Scholar 

  13. Darian-Smith I, Darian-Smith C, Galea M, Pepperell R (1991) Thalamocortical connections with sensorimotor areas in the mature and newborn macaque monkeys. In: Humphrey DR, Freund H-J (eds) Motor control: concepts and issues. Wiley, Chichester, pp 181–197

    Google Scholar 

  14. Denny-Brown D, Chambers RA (1958) The parietal lobes and behavior. Res Pub Assoc Res Mental Dis 36:35–117

    CAS  Google Scholar 

  15. Desmedt JE, Tomberg C (1989) Mapping early somatosensory evoked potentials in selective attention: critical evaluation of the control conditions used for titrating by difference the cognitive P30, P40, P100, and N140. Electroencephalogt Clin Neurophysiol 74:321–346

    Article  CAS  Google Scholar 

  16. Duhamel J-R, Colby CL, Goldberg ME (1991) Congruent representations of visual and somatosensory space in single neurons of monkey ventral intra-parietal cortex (area VIP). In: Paillard J (ed) Brain and space. Oxford University Press, Oxford, pp 223–236

    Google Scholar 

  17. Gardner EP (1988) Somatosensory cortical mechanisms of feature detection in tactile and kinesthetic discrimination. Can J Physiol Pharmacol 66:439–454

    Article  PubMed  CAS  Google Scholar 

  18. Gardner EP, Palmer CI (1989) Simulation of motion on the skin. II. Cutaneous mechanoreceptor coding of the width and texture of bar patterns displaced across the OPTACON. J Neurophsyiol 62:1437–1460

    CAS  Google Scholar 

  19. Garraghty PE, Kaas JH (1991a) Large-scale functional reorganization in adult monkey cortex after peripheral nerve injury. Proc Natl Acad Sci U S A 88:6976–6980

    Article  PubMed  CAS  Google Scholar 

  20. Garraghty PE, Kaas JH (1991b) Functional reorganization in adult monkey thalamus after peripheral nerve injury. Neurorep 2:747–750

    Article  CAS  Google Scholar 

  21. Garraghty PE, Kaas JH (1992) Dynamic features of sensory and motor maps. Curr Opin Neurobiol 2:522–527

    Article  PubMed  CAS  Google Scholar 

  22. Gilbert CD (1993) Rapid dynamic changes in adult cerebral cortex. Curr Opin Neurobiol 3:100–103

    Article  PubMed  CAS  Google Scholar 

  23. Green MW, Selman JE (1993) Review article: The medical management of trigeminal neuralgia. Headache 31:588–592

    Article  Google Scholar 

  24. Hampf G, Bowsher D, Wells C, Miles J (1990) Sensory and autonomic measurements in idiopathic trigeminal neuralgia before and after radiofrequency thermocoagulation: differentiation from some other causes of facial pain. Pain 40:241–248

    Article  PubMed  CAS  Google Scholar 

  25. Hartline HK, Ratliff F (1957) Inhibitory interaction of receptor units in the eye of Limulus. J Gen Physiol 40:357–376

    Article  PubMed  CAS  Google Scholar 

  26. Heung SN, Leem JW, Chung JM (1993) Abnormalities of mechanoreceptors in a rat model of neuropathic pain: possible involvement in mediating mechanical allodynia. J Neurophysiol 70:522–528

    Google Scholar 

  27. Hikosaka O, Tanaka M, Sakamoto M, Iwamura Y (1985) Deficits in manipulative behaviors induced by local injections of muscimol in the first somatosensory cortex of the conscious monkey. Brain Res 325:375–380

    Article  PubMed  CAS  Google Scholar 

  28. Hsiao SS, O’Shaughnessy DM, Johnson KO (1993) Effects of selective attention on spatial form processing in monkey primary and secondary somatosensory cortex. J Neurophysiol 70:444–447

    PubMed  CAS  Google Scholar 

  29. Hulliger M, Nordh E, Thelin A-E, Vallbo A (1979) The responses of afferent fibres from the glabrous skin of the hand during voluntary finger movements in man. J Physiol (Lond) 291:233–249

    CAS  Google Scholar 

  30. Hyvärinen J, Poranen A (1974) Function of the parietal associative area 7 as revealed from cellular discharges in awake monkeys. Brain 97:673–692

    Article  PubMed  Google Scholar 

  31. Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1983) Functional subdivisions representing different finger regions in area 3 of the first somatosensory cortex of the conscious monkey. Exp Brain Res 51:315–326

    Google Scholar 

  32. Iwamura Y, Tanaka M, Sakamoto M, Hikosaka O (1985) Vertical neuronal arrays in the post-central gyrus signaling active touch: a receptive field study in the conscious monkey. Exp Brain Res 58:412–420

    PubMed  CAS  Google Scholar 

  33. Jankowska E (1992) Interneuronal relay in spinal pathways from proprioceptors. Prog Neurobiol 38:335–378

    Article  PubMed  CAS  Google Scholar 

  34. Jeannerod M (1991) A neurophysiological model for the directional coding of reaching movements. In: Paillard J (ed) Brain and space, Oxford University Press, Oxford, pp 47–69

    Google Scholar 

  35. Jenkins WM, Merzenich MM, Ochs MT, Allard T, Guic-Rocbles E (1990) Functional reorganization of primary somatosensory cortex in adult owl monkeys after behaviorally controlled tactile stimulation. J Neurophysiol 63:82–104

    PubMed  CAS  Google Scholar 

  36. Jiménez I, Rudomin P, Solodkin M (1987) Mechanisms involved in the depolarization of cutaneous afferents produced by segmental and descending inputs in the cat spinal cord. Exp Brain Res 69:195–207

    Article  PubMed  Google Scholar 

  37. Jones EG (1990) The role of afferent activity in the maintenance of primate neocortical function. J Exp Biol 153:155–176

    PubMed  CAS  Google Scholar 

  38. Johansson RS (1991) How is grasping modified by somatosensory input? In: Humphrey DR, Freund H-J (eds) Motor control: concepts and issues. Wiley, Chichester, pp 331–355

    Google Scholar 

  39. Johansson RS, Cole KJ (1992) Sensory-motor coordination during grasping and manipulative actions. Curr Opin Neurobiol 2:815–823

    Article  PubMed  CAS  Google Scholar 

  40. Johansson RS, Vallbo ÅB (1983) Tactile sensory coding in the glabrous skin of the human hand. Trends Neurosci:27–32

    Google Scholar 

  41. Johnson KO, Hsiao SS (1992) Neural mechanisms of tactual form and texture perception. Annu Rev Neurosci 15:227–250

    Article  PubMed  CAS  Google Scholar 

  42. Juliano SL, Ma W, Eslin D (1991) Cholinergic depletion prevents expansion of topographic maps in somatosensory cortex. Proc Natl Acad Sci U S A 88:780–784

    Article  PubMed  CAS  Google Scholar 

  43. Kalaska JF (1991) What parameters of reaching are encoded by discharges of cortical cells? In: Humphrey DR, Freund H-J (eds) Motor control: concepts and issues. Wiley, Chichester, pp 307–330

    Google Scholar 

  44. Kandel ER, Schwartz JH, Jessell TM (1991) Principles of neural science, 3rd edn. Elsevier, New York

    Google Scholar 

  45. Kano M, Iino K, Kano M (1991) Functional reorganization of adult cat somatosensory cortex is dependent on NMDA receptors. Neurorep 2:77–80

    Article  CAS  Google Scholar 

  46. Katusic S, Beard CM, Bergstralh E, Kurland LT (1990) Incidence and clinical features of trigeminal neuralgia, Rochester, Minnesota, 1945–1984. Ann Neurol 27:89–95

    Article  PubMed  CAS  Google Scholar 

  47. Katz J (1992) Psychophysiological contributions to phantom limbs. Can J Psychiatry 37:282–298

    PubMed  CAS  Google Scholar 

  48. Knibestöl M (1975) Stimulus-response functions of slowly adapting mechanoreceptors in human glabrous skin areas. J Physiol (Lond) 245:63–80

    Google Scholar 

  49. LaMotte RH, Mountcastle VB (1979) Disorders in somesthesis following lesions of parietal lobe. J Neurophysiol 42:400–419

    PubMed  CAS  Google Scholar 

  50. Leinonen L, Hyvärinen J, Nyman G, Linnankoski I (1979) Functional properties of neurons in lateral part of associative area 7 in awake monkeys. Exp Brain Res 34:299–320

    PubMed  CAS  Google Scholar 

  51. Loewenstein WR, Mendelsohn M (1965) Components of receptor adaptation in a Pacinian corpuscle. J Physiol (Lond) 177:377–397

    CAS  Google Scholar 

  52. Loewenstein WR, Skalak R (1965) Mechanical transmission in a Pacinian corpuscle. An analysis and a theory. J Physiol (Lond) 182:346–378

    Google Scholar 

  53. Mackel R (1988) Conduction of neural impulses in human mechanoreceptive cutaneous afferents. J Physiol (Lond) 401:597–615

    CAS  Google Scholar 

  54. Merzenich MM, Recanzone G, Jenkins WM, Allard TT, Nudo RJ (1988) Cortical representational plasticity. In: Rakic P, Singer W (eds) Neurobiology of neocortex. Wiley, Chichester, pp 41–67

    Google Scholar 

  55. Merzenich MM, Sameshima K (1993) Cortical plasticity and memory. Curr Opin Neurobiol 3:187–196

    Article  PubMed  CAS  Google Scholar 

  56. Mesulam M-M, Mufson EJ (1983) Neural inputs into the nucleus basalis of the substantia innominata (Ch4) in the rhesus monkey. Brain 107:253–274

    Article  Google Scholar 

  57. Metherate R, Tremblay N, Dykes RW (1988) Transient and prolonged effects of acetylcholine on responsiveness of cat somatosensory cortical neurons. J Neurophysiol 59:1253–1276

    PubMed  CAS  Google Scholar 

  58. Mitchell SW (1871) Phantom limbs. Lippencotts Mag Pop Lit Sci 8:563–569

    Google Scholar 

  59. Montague PR, Gally JA, Edelman GM (1991) Spatial signalling in the development and function of neural connections. Cerebr Cortex 1:199–220

    Article  CAS  Google Scholar 

  60. Mountcastle VB (1984) Central nervous mechanisms in mechanoreceptive sensibility. In: Darian-Smith I (ed) The nervous system, vol III, sensory processes, part 2 (Handbook of physiology). American Physiological Society, Bethesda

    Google Scholar 

  61. Mountcastle VB (1988) Dynamic neuronal operations within the somatic sensory cortex. In: Rakic P, Singer W (eds) Neurobiology of neocortex. Wiley, Chichester, pp 253–267

    Google Scholar 

  62. Mountcastle VB, Powell TPS (1959) Neural mechanisms subserving cutaneous sensibility, with special reference to the role of afferent inhibition in sensory perception and discrimination. Bull Johns Hopkins Hosp 105:201–232

    PubMed  CAS  Google Scholar 

  63. Mountcastle VB, Talbot WH, Kornhuber HH (1966) The neural transformation of mechanical stimuli delivered to the monkey’s hand. In: de Reuck AVS, Knight J (eds) CIBA Foundation symposium on touch, heat and pain, Churchill, London, pp 325–351

    Google Scholar 

  64. Mountcastle VB, Lynch JC, Georgopoulos A, Sakata H, Acuna C (1975) Posterior parietal association cortex of the monkey: command function for operations within extrapersonal space. J Neurophysiol 38:871–908

    PubMed  CAS  Google Scholar 

  65. Mountcastle VB, Steinmetz MA, Romo R (1990) Frequency discrimination in the sense of flutter: psychophysical measurements correlated with postcentral events in behaving monkeys. J Neurosci 10:3032–3044

    PubMed  CAS  Google Scholar 

  66. Mountcastle VB, Atluri PP, Romo R (1992) Selective output-discriminative signals in the motor cortex of waking monkeys. Cerebral Cortex 2:277–294

    Article  PubMed  CAS  Google Scholar 

  67. Na HS, Leem JW, Chung JM (1993) Abnormalities of mechanoreceptors in a rat model of neuropathic pain: possible involvement in mediating mechanical allodynia. J Neurophysiol 70:522–528

    PubMed  CAS  Google Scholar 

  68. Nicoll RA, Malenka RC, Kauer JA (1990) Functional comparison of neurotransmitter receptor subtypes in mammalian central nervous system. Physiol Rev 70:513–565

    PubMed  CAS  Google Scholar 

  69. Nordin M (1990) Low-threshold mechanoreceptive and nociceptive units with unmyelinated (C) fibres in the human supraorbital nerve. J Physiol (Lond) 229–240

    Google Scholar 

  70. Ochoa J, Torebjörk E (1983) Sensations evoked by intraneural microstimulation of single mechanoreceptor units innervating the human hand. J Physiol (Lond) 342:633–654

    CAS  Google Scholar 

  71. Paillard J (1991) Motor and representational framing of space. In: Paillard J (ed) Brain and space. Oxford University Press, Oxford, pp 163–182

    Google Scholar 

  72. Pettit MJ, Schwark HD (1993) Receptive field reorganization in dorsal column nuclei during temporary denervation. Science 262:2054–2056

    Article  PubMed  CAS  Google Scholar 

  73. Phillips JR, Johnson KO, Hsiao SS (1988) Spatial pattern representation and transformation in monkey somatosensory cortex. Proc Natl Acad Sci 85:1317–1321

    Article  PubMed  CAS  Google Scholar 

  74. Phillips JR, Johansson RS, Johnson KO (1990) Representation of braille characters in human nerve fibres. Exp Brain Res 81:589–592

    Article  PubMed  CAS  Google Scholar 

  75. Pons TP, Garraghty PE, Ommaya AK, Kaas JH, Taub E, Mishkin M (1991) Massive cortical reorganization after sensory in adult macaques. Science 252:1857–1860

    Article  PubMed  CAS  Google Scholar 

  76. Poulos DA, Mei J, Horch KW, Tuckett RP, Wei JY, Cornwall MC, Burgess PR (1984) The neural signal for the intensity of a tactile stimulus. J Neurosci 4:2016–2024

    PubMed  CAS  Google Scholar 

  77. Pubols BH (1988) Spread of skin deformation and mechanoreceptor discharge. Prog Brain Res 74:263–270

    Article  PubMed  Google Scholar 

  78. Ramachandran VS, Rogers-Ramachandran D, Stewart M (1992) Perceptual correlates of massive cortical reorganization. Science 258:1159–1160

    Article  PubMed  CAS  Google Scholar 

  79. Recanzone GH, Allard TT, Jenkins WM, Merzenich MM (1990) Receptive-field changes induced by peripheral nerve stimulation in SI of adult cats. J Neurophysiol 63:1213–1225

    PubMed  CAS  Google Scholar 

  80. Recanzone GH, Merzenich MM, Dinse HR (1992a) Expansion of the cortical representation of a specific skin field in primary somatosensory cortex by intracortical microstimulation. Cerebr Cortex 2:181–196

    Article  CAS  Google Scholar 

  81. Recanzone GH, Merzenich MM, Jenkins WM, Kamil AG, Dinse HR (1992b) Topographic reorganization of the hand representation in cortical area 3b of owl monkeys trained in a frequency-discrimination task. J Neurophysiol 67:1031–1056

    PubMed  CAS  Google Scholar 

  82. Rhoades RW, Wall JT, Chiaia NL, Bennett-Clarke CA, Killackey HP (1993) Anatomical and functional changes in the Organization of the cuneate nucleus of adult rats after fetal forelimb amputation. J Neurosci 13:1106–1119

    PubMed  CAS  Google Scholar 

  83. Roland PE, Eriksson L, Widén L, Stone-Elander S (1989) Changes in regional cerebral oxidative metabolism induced by tactile learning and recognition in man. Eur J Neurosci 1:3–18

    Article  PubMed  Google Scholar 

  84. Russchen FT, Amaral DG, Price JL (1985) The afferent connections of the substantia innominata in the monkey, macaca fascicularis. J Comp Neurol 242:1–27

    Article  PubMed  CAS  Google Scholar 

  85. Sinclair RJ, Burton H (1993) Neuronal activity in the second somatosensory cortex of monkeys (Macaca mulatta) during active touch of gratings. J Neurophysiol 70:331–350

    PubMed  CAS  Google Scholar 

  86. Snow PJ, Nudo RJ, Rivers W, Jenkins WM, Merzenich MM (1988) Somatotopically inappropriate projections from thalamocortical neurons to SI cortex of the cat demonstrated by the use of intracortical microstimulation. Somatosens Res 5:349–372

    Article  PubMed  CAS  Google Scholar 

  87. Srinivasan MA, Whitehouse JM, LaMotte RH (1990) Tactile detection of slip: surface microgeometry and peripheral neural codes. J Neurophysiol 63:1323–1332

    PubMed  CAS  Google Scholar 

  88. Stein JF (1991) Space and the parietal association areas. In: Paillard J (ed) Brain and space. Oxford University Press, Oxford, pp 185–222

    Google Scholar 

  89. Vallbo ÅB, Olsson KÅ, Westberg K-G, Clark FJ (1984) Microstimulation of single tactile afferents from the human hand. Sensory attributes related to unit type and properties of receptive fields. Brain 107:727–749

    Article  PubMed  Google Scholar 

  90. Wall JT (1988) Variable organization in cortical maps of the skin as an indication of the lifelong adaptive capacities of circuits in the mammalian brain. Trends Neurosci 11:549–557

    Article  PubMed  CAS  Google Scholar 

  91. Walmsley B (1991) Central synaptic transmission: studies at the connection between primary afferent fibres and dorsal spinocerebellar tract (DSCT) neurones in Clarke’s column of the spinal cord. Prog Neurobiol 36:391–423

    Article  PubMed  CAS  Google Scholar 

  92. Warren S, Hamalainen HA, Gardner EP (1986) Objective classification of motion- and direction-sensitive neurons in primary somatosensory cortex of awake monkeys. J Neurophysiol 56:598–622

    PubMed  CAS  Google Scholar 

  93. Webster HH, Hanisch U-K, Dykes RW, Biesold D (1991) Basal forebrain lesions with or without reserpine injection inhibit cortical reorganization in rat hindpaw primary somatosensory cortex following sciatic nerve section. Somatosens Motor Res 8:327–346

    Article  CAS  Google Scholar 

  94. Werner G, Mountcastle VB (1965) Neural activity in mechanoreceptive cutaneous afférents: stimulus-response relations, Weber functions, and information transmission. J Neurophysiol 28:359–397

    PubMed  CAS  Google Scholar 

  95. Zarzecki P, Witte S, Smits E, Gordon DC, Kirchberger P, Rasmusson DD (1993) Synaptic mechanisms of cortical representational plasticity: somatosensory and corticocortical EPSPs in reorganized raccoon SI cortex. J Neurophysiol 69:1422–1432

    PubMed  CAS  Google Scholar 

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Windhorst, U. (1996). Tactile Senses. In: Greger, R., Windhorst, U. (eds) Comprehensive Human Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60946-6_33

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  • DOI: https://doi.org/10.1007/978-3-642-60946-6_33

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