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Hormones Modulate Environmental Control of a Changing Brain

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Comprehensive Human Physiology

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Abstract

One of the fundamental problems of modern biology is understanding the link between the genetic endowment (sometimes called “nature”) and the environment (sometimes called “nurture”). Countless arguments over the past century have centered on the question “Which is more important for shaping the individual: nature or nurture?” Unfortunately, most of these arguments have generated more heat than light, owing to a fundamental misunderstanding of the relationship between genes and the environment, namely, the belief that gene expression was autonomous and that the environment produced its effects via processes that were independent of the genome. What changed everything was the discovery that, in reacting to the environment inside and outside of the body, the organism uses chemical signals to direct the variable expression of genes. Among the most important and ubiquitous chemical signals are hormones.

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  1. B. S. McEwen
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  1. Physiologisches Institut, Universität Freiburg, Hermann-Herder-Str. 7, 79104, Freiburg, Germany

    Rainer Greger

  2. Faculty of Medicine, Department of Clinical Neurosciences, University of Calgary, 3330 Hospital Drive N.W., T2N 4N1, Calgary, Alberta, Canada

    Uwe Windhorst

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© 1996 Springer-Verlag Berlin Heidelberg

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McEwen, B.S. (1996). Hormones Modulate Environmental Control of a Changing Brain. In: Greger, R., Windhorst, U. (eds) Comprehensive Human Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60946-6_24

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  • DOI: https://doi.org/10.1007/978-3-642-60946-6_24

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