Skip to main content

Pulmonary and Bronchial Circulation

  • Chapter
Comprehensive Human Physiology

Abstract

Pulmonary blood flow is the denominator of the ventilation-perfusion ratio, V A/Q, and is of equal importance with breathing in determining the overall efficiency of pulmonary gas exchange (Table 104.1). A major hemodynamic difference between the systemic and pulmonary circulations [4,6] is that the entire cardiac output passes through the lungs — which has only about 1% of the body mass — and it does so with a mean pulmonary arterial-to-left atrial driving pressure that is less than one-tenth that of the systemic circulation. The difference is that in the pulmonary circulation the small muscular arteries and arterioles, both by their enormous number and their low basal smooth muscle tone, contribute much less to total flow resistance than their systemic counterparts.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 349.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 449.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bhattacharya J, Staub NC (1980) Direct measurement of microvascular pressures in the isolated perfused dog lung. Science 210:327–328

    Article  PubMed  CAS  Google Scholar 

  2. Deffenbach ME, Charan NB, Lakshminarayan S, Butler J (1987) The bronchial circulation: small, but a vital attribute of the lung. Am Rev Respir Dis 135:463–481

    Google Scholar 

  3. Gillis CN (1986) Pharmacological aspects of metabolic processes in the pulmonary microcirculation. Annu Rev Pharmacol Toxicol 26:183–200

    Article  PubMed  CAS  Google Scholar 

  4. Grover RF, Wagner WW Jr, McMurtry I, Reeves JT (1984) Pulmonary circulation. In: Shepherd JT, Abboud FM (eds) Handbook of physiology: the cardiovascular system. III. American Physiological Society, Bethesda, pp 103–136

    Google Scholar 

  5. Gunteroth WG, Luchtel DL, Kawabori I (1982) Pulmonary micro-circulation — tubules rather than sheet and post. J Appl physiol 53:510–515

    Google Scholar 

  6. Harris P, Heath D (1978) The human pulmonary circulation, 2nd edn. Livingston, Edinburgh

    Google Scholar 

  7. Hyman AL, Spannhake EW, Kadowitz PJ (1978) Prostaglandins and the lung. Am Rev Respir Dis 117:111–136

    PubMed  CAS  Google Scholar 

  8. Mitzner W (1983) Resistance of the pulmonary circulation. Clin Chest Med 4:127–137

    PubMed  CAS  Google Scholar 

  9. Staub NC (1984) Pathophysiology of pulmonary edema. In: Staub NC, Taylor AE (eds) Edema. Raven, New York

    Google Scholar 

  10. Staub NC (1990) Pathways for lung liquid clearance. In: Brigham KL, Stahlman MT (eds) Respiratory distress syndromes: molecules to man. Vanderbilt, Nashville, pp 33–43

    Google Scholar 

  11. West JB, Dollery CT, Naimark A (1964) Distribution of blood flow in isolated lung: relation to vascular and alveolar pressures. J Appl Physiol 19:713–724

    PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Staub, N.C., Dawson, C.A. (1996). Pulmonary and Bronchial Circulation. In: Greger, R., Windhorst, U. (eds) Comprehensive Human Physiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60946-6_105

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-60946-6_105

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64619-5

  • Online ISBN: 978-3-642-60946-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics