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Thermoradiotherapy of Uterine Carcinoma

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Thermoradiotherapy and Thermochemotherapy

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

In 1993, about 48 000 new cases of invasive uterine carcinoma were observed, comprising 14000 cases of cervical and 34 000 of endometrial cancer. The mortality is disproportionate to the incidence, with an estimated 6000 deaths from cervical and 4000 from endometrial cancer. Overall, the incidence and mortality have steadily decreased over the years due to early detection and screening programs including Pap tests and physical examinations (American Cancer Society 1993)

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References

  • Akuta K, Hiraoka M, Jo S, et al. (1989) A newly developed interstitial applicator for RF current heating,. In: Sugahara T, Saito M (eds) Hyperthermic oncology 1988, vol 1. Taylor & Francis, London, pp 878 – 880

    Google Scholar 

  • American Cancer Society (1993) Cancer facts and figures 1993,. American Cancer Society, Atlanta Aristizabal SA (1985) Interstitial parametrial irradiation in cancer of the cervix stages IIB-IIIB: analysis of pelvic control and complications. Int J Endocurie/Hyperther mia Oncol 1: 41 – 48

    Google Scholar 

  • Aristizabal SA, Oleson JR (1984) Combined interstitial irradiation and localized current field hyperthermia: results and conclusions from clinical studies. Cancer Res 44(suppl): 4757s–4760s

    Google Scholar 

  • Awwad HK, Naggar ME, Mocktar N, Barsoum M (1986) Intercapillary distance measurement as an indicator of hypoxia in carcinoma of the cervix uteri. Int J Radat Oncol Biol Phys 12: 1329 – 1333

    Article  CAS  Google Scholar 

  • Brenner DI, Huang Y, Hall EJ (1991) Fractionated high-dose-rate versus low-dose-rate regimens for intracavitary brachytherapy of the cervix: equivalent regimens for combined brachytherapy and external irradiation. Int J Radiat Oncol Biol Phys 21: 1415 – 1423

    Article  PubMed  CAS  Google Scholar 

  • Coughlin CT, Ryan TP, Stafford JH (1991) Interstitial thermoradiotherapy: the Dartmouth experience 1981–1990. In: Chapman JD, Dewey WC, Whitmore GF (eds) Radiation research - a twentieth-century perspective, vol 1. Academic Press, San Diego, p 386 [P 31 02 WP] (abstract) Datta NR, Rose AK, Kapoor HK (1987) Thermoradiotherapy in the management of carcinoma of the cervix IIIB: a controlled clinical study,. Indian Med Gazette 121: 68 – 71

    Google Scholar 

  • Deurloo IIK, Visser AG, Ruifrok ACC, Lakeman RF, van Rhoon GC, Levendag PC (1989) Radiofrequency interstitial hyperthermia: a multicentric program of quality assessment and clinical trials. In: Sugahara T, Saito M (eds) Hyperthermic Oncology 1988, vol 1. Taylor & Francis, London,, pp 864 – 875

    Google Scholar 

  • Diederich CJ, Hynynen KH (1983) Ultrasound technology for interstitial hyperthermia. In: Seegenschmiedt MH, Sauer R (eds) Interstitial & intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 55 – 62

    Google Scholar 

  • Dische S, Anderson PJ, Sedly R, Watson ER (1983) Carcinoma of the cervix - anaemia, radiotherapy and hyperbaric oxygen,. Br J Radiol 56: 251 – 255

    Article  PubMed  CAS  Google Scholar 

  • Emami B, Perez CA, Konefal J, et al. (1987) Interstitial thermoradiotherapy in treatment of malignant tumors. Int J Hyperthermia 3: 107 – 118

    Article  PubMed  CAS  Google Scholar 

  • Feldmann JH, Sack H (1992) Achieved temperature distributions in dependency on applicator technique and/or perfusions values. Strahlenther Onkol 168: 657 – 659

    Google Scholar 

  • Feldmann HJ, Molls M, Heinemann H-G, Romanowski R, Stuchke M, Sack H (1993) Thermoradiotherapy in locally advanced deep seated tumors - thermal parameters and treatment results. Radiother Oncol 26: 38 – 44

    Article  PubMed  CAS  Google Scholar 

  • Gaddis O (1983) Treatment of cervical carcinoma employing a template for transperineal interstitial 192 iridium brachytherapy,. Int J Radiat Oncol Biol Phys 9: 819 – 824

    Article  PubMed  Google Scholar 

  • Gautherie M, Cosset JM, Gerard JP, et al. (1989) Radio- frequency interstitial hyperthermia: a multi-centric program of quality assessment and clinical trials. In: Sugahara T, Saito M (eds) Hyperthermic oncology 1988, vol 2. Taylor & Francis, London, pp 711 – 714

    Google Scholar 

  • Grigsby PW, Emami B (1993) Interstitial thermoradiotherapy for pelvic tumors: the Washington University experience. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 265 – 270

    Google Scholar 

  • Hand JW, Blake PR, Hopewell JW, Lambert HW, Field SB (1982) A coaxial applicator for intra-cavitary hyperthermia of carcinoma of the cervix. In: Robinson JE (ed) Biomedical Thermolog. Liss, New York, pp 635 – 639

    Google Scholar 

  • Handl-Zeller L (1993) Clinical experience of interstitial thermoradiotherapy using hot water perfusion techniques. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 211 – 222

    Google Scholar 

  • Hietschold V, Klengel S, Kohler K (1993) Simultaneous dynamic measurement of tissue contrast enhancement and perfusion at 0.5 Tesla: method and postprocessing. In: Proceedings of the Society of Magnetic Resonance in medicine, vol 2, 12th Annual Scientific Meeting, August 14–20, 1993, New York

    Google Scholar 

  • Herrmann T, Christen N, Alheit HD (1993) Gynakolo-gische Brachytherapie - von Low-dose-rate zu Hightech,. Strahlenther Onkol 169: 141 – 151

    PubMed  CAS  Google Scholar 

  • Höckel M, Knoop C, Schlenger K, et al. (1993) Intra- tumoral p02 predicts survival in advanced cancer of the uterine cervix. Radiother Oncol 26: 45 – 50

    Article  PubMed  Google Scholar 

  • Hornback NB, Shupe RE, Shidnia H, Marshall CV, Lauer T (1986) Advanced stage IIIB cancer of the cervix: treatment by hyperthermia and radiation. Gynecol Cncol 23: 160 – 167

    Article  CAS  Google Scholar 

  • Kolstadt P (1965) The development of the vascular bed in tumours as seen in squamous-cell carcinomas of the cervix uteri. Br J Radiol 38: 216 – 223

    Article  Google Scholar 

  • Kottmeier HL (ed) (1988) Annual report on the results of treatments in gynaecological cancer, volume XIX. International Federation of Gynecology and Obstetrics, Stockholm

    Google Scholar 

  • Lagendijk JJW, Mooibroek J, Crezee (1993) Future developments in respect of thermal modeling, treatment planning, and tretment control for interstitial hyperthermia. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Spring, Berlin Heidelberg New York, pp 155 – 159

    Google Scholar 

  • Li DJ, Chou CK, Luk KH, Wang JH, Xie CF, McDougall JA, Huang GZ (1991) Design of intracavitary mirco-wave applicators for the treatment of uterine cervix carcinoma. Int J Hyperthermia 7: 693 – 701

    Article  PubMed  CAS  Google Scholar 

  • Loffel J, Stahl H, Wust P, Riess H, Felix R (1993) Clinical experience with regional RF-hyperthermia: an overview. In: Proceedings of the 11th Annual Scientific Meeting of the ESHO, June 16–17, 1993

    Google Scholar 

  • Brussels Lowrey GC, Mendenhall WM, Million RR (1992) Stage IB or IIA-B carcinoma of the intact uerine cervix treated with irradiation: a multivariate analysis. Int J Radiat Oncol Biol Phys 24: 205 – 210

    PubMed  CAS  Google Scholar 

  • Marchal C, Nadi M, Hofstetter S, Bey P, Pernot M, Prieur G (1989) Practical interstitial method of heating operating at 27.12 MHz. Int J Hyperthermia 5: 451 – 466

    Article  PubMed  CAS  Google Scholar 

  • Martinez A, Edmundson GK, Cox RS (1985) Combination of external beam irradiation and multiple-side perineal applicator (MUPIT) for treatment of locally advanced or recurrent prostatic, anorectal and gynecological malignancies. Int J Radiat Oncol Biol Phys 11: 391 – 398

    Article  PubMed  CAS  Google Scholar 

  • Martinez A, Gersten D, Corry P (1993) Clinical rationale for interstitial thermoradiotherapy of gynecological tumors: review of clinical results and own experiences with continuous mild hyperthermia. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 179 – 186

    Google Scholar 

  • Meyer JL (1984a) Hyperthermia as an anticancer modality - a historical perspective,. Front Radiat Ther Oncol 18: 1 – 22

    CAS  Google Scholar 

  • Meyer JL (1984b) Ultrasound hyperthermia: the Stanford experience. Front Radiat Ther Oncol 18: 126 – 135

    CAS  Google Scholar 

  • Müller C (1912) Therapeutische Erfahrungen an 100 mit Kombination von Rontgenstrahlen und Hochfrequenz, resp. Diathermie behandelten bosartigen Neubildungen. Münch Medizin Wschr 28: 1546 – 1549

    Google Scholar 

  • Nagano H, Tanohata K, Kusaba T, Kakehi M (1993) Radiohyperthermia for stage III, IV and recurrent uterine carcinioma. 16th Intern. Symposium on Clinical Hyperthermia, June 13–16, 1993, Kyoto

    Google Scholar 

  • Nagata K, Yamamoto K, Shiga T, Tanaka Y (1993) Clinical results of radiofrequency hyperthermia for malignant pelvic tumors. 16th Intern. Symposium on Clinical Hyperthermia, June 13–16, 1993, Kyoto

    Google Scholar 

  • Notter M, Schwegler N (1992) Monitoring of deep hyperthermia: what means a complete remission ? Strahlenther Onkol 168: 657 – 659

    Google Scholar 

  • Overgaard J (1989) The current and potential role of hyperthermia. Int J Radiat Oncol Biol Phys 16: 535-549 Overgaard J, Horsmann MR ( 1992 ) Hyperthermia. In: The ESTRO book of basic clinical radiobiolog, pp 177 – 188

    Google Scholar 

  • Parisi S, Raguso A, Portaluri M, Maiorana A, Vittori Antisari P (1990) Intracavitary hyperthermia combined with HDR afterloading irradiation in vaginal recurrences of cervical carcinoma. Adv Exp Med Biol 267: 429 – 432

    PubMed  CAS  Google Scholar 

  • Perez CA (1980) Radiation therapy alone in the treatment of the uterine cervix,. I. Analysis of tumor recurrence. Cancer 51: 1393 – 1402

    Article  Google Scholar 

  • Perez CA, Grigsby PW, Nene SM, Camel HM, Galakatos A, Kao MS, Lockett MA (1992) Effect of tumor size on prognosis of carcinoma of the uterine cervix treated with irradiation alone. Cancer 69: 2796 – 2806

    Article  PubMed  CAS  Google Scholar 

  • Probert JC, Saben HS, Gregory JC (1977) Use of the pig for assessing damage in the locally treated pelvis and abdomen,. Int J Radiat Oncol Biol Phys 2: 491 – 503

    Article  PubMed  CAS  Google Scholar 

  • Petrovich Z, Langholz B, Lam K, et al. (1989) Interstitial microwave hyperthermia combined with iridium-192 radiotherapy for recurrent tumors. Am J Clin Oncol 12: 264 – 268

    Article  PubMed  CAS  Google Scholar 

  • Puthawala AA, Syed AMN, Khalid MA, Rafie S, McNamara CS (1985) Interstitial hyperthermia for recurrent malignancies. Endocurietherapy/Hyperthermia Oncol 1: 125 – 131

    Google Scholar 

  • Roos D (1993) Review of intracavitary hyperthermia techniques. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 75 – 82

    Google Scholar 

  • Sapozink MD, Joszef G, Astrahan MA, Gibbs FA Jr, Petrovich Z, Stewart JR (1990) Adjuvant pelvic hyperthermia in advanced cervical carcinoma,. I. Feasibility, thermometry and device comparison. Int J Hypertherma 6: 985 – 996

    Article  CAS  Google Scholar 

  • Schorcht J (1994) Radiothermotherapy of cervical carcinoma,. In: Fietkau R, Mould RF (eds) Brachytherapy state of the art in Germany. Proceedings Deutsche Brachytherapie-Konferenz ’93, Naumburg/Saale, September 23–25, 1993, Chapter lONucletron, Veenendaal, pp 81 – 87

    Google Scholar 

  • Schorcht J, Zimmermann M, Redmann M, Eberhardt HJ (1989) Erste Erfahrungen mit der kombinierten hochdo- sierten Afterloading-Kurzzeittherapie und Hyperthermic beim nicht-operierten Zervixkarzinom. Radiobiol Radiother 30: 386 – 390

    CAS  Google Scholar 

  • Seegenschmiedt MH (1993) Clinical experience of interstitial thermoradiotherapy using microwave techniques. In: Seegenschmiedt MH, Sauer, R (eds) Interstitial and intracavitary thermo-radiotherapy. Springer, Berlin Heidelberg New York, pp 193-210 Seegenschmiedt MH, Sauer R (1992) The current role of interstitial thermoradiotherapy. Strahlenther Onkol 168: 119 – 140

    Google Scholar 

  • Seegenschmiedt MH, Sauer R, Brady LW, Karlsson UL(1990) Interstitial thermoradiotherapy: review on current techniques and clinical experience. Am J Clin Oncol 13: 352–363

    Google Scholar 

  • Seegenschmiedt MH, Sauer R, Miyamoto C, Brady LW (1993) Interstitial thermoradiotherapy for pelvic tumors: a co-operative phase 1-2 study. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berling Heidelberg New York, pp 271 – 288

    Google Scholar 

  • Seegenschmiedt MH, Martus P, Fietkau R, Iro H, Brady LW, Sauer R (1994) Multivariate analysis of prognostic parameters using interstitial thermoradiotherapy (IHT- IRT): tumor and treatment variables predict outcome. Int J Radiat Oncol Biol Phys 29: 1049 – 1063

    Article  PubMed  CAS  Google Scholar 

  • Sharma S, Patel FD, Sandhu APS, Gupta BD, Yadav NS (1989) A prospective randomized study of local hyperthermia as a supplement and radiosensitizer in treatment of carcinoma of the cervix with radiotherap Endocurie- therapie/Hyperthermia Oncol 5: 151 – 159

    Google Scholar 

  • Sharma S, Sandhu APS, Patel FD, Ghoshal S, Gupta BD, Yadav NS (1990) Side-effects of local hyperthermia: results of a prospectively randomized clinical study. Int J Hyperthermia 6: 279 – 285

    Article  PubMed  CAS  Google Scholar 

  • Sharma S, Singhal S, Sandhu APS, Ghoshal S, Gupta BD, Yadav NS (1991a) Local thermoradiotherapy in carcinoma cervix: improved local control versus increased incidence of distant meta-stasis. Asia Oceania J Obstet Gynecol 17: 5 – 12

    Article  CAS  Google Scholar 

  • Sharma S, Patel FD, Gupta PD, Negi PS, Ayyagary S (1991b) Clinical trial of LDR versus HDR brachytherapy in carcinoma of the cervix. Selectron Activity 2: 59 – 64

    Google Scholar 

  • Shimm DS, Kittelson JM, Oleson JR, Aristizabal JA, Barlow LC, Cetas TC (1990) Interstitial thermoradiotherapy: thermal dosimetry and clinical results. Int J Radiat Oncol Biol Phys 18: 383 – 387

    Article  PubMed  CAS  Google Scholar 

  • Siracky J, Siracka E, Kovac R, Revesz L (1988) Prognostic significance of vascular density and a malignancy grading in radiation treated uterine cervix carcinoma. Neoplasma 35: 289 – 296

    PubMed  CAS  Google Scholar 

  • Stea B, Shimm D, Cetas TC (1993) Clinical experience of interstitial thermoradiotherapy using ferromagnetic implant techniques. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 223 – 232

    Google Scholar 

  • Sullivan MF, Beamer JL, Cross FT, Lund JE, Mahony TD, Endres GW, Buschbom RL (1980) Pathologic effects of intracavitary irradiation with Californium-252. Int J Radiat Oncol Biol Phys 6: 1613 – 1627

    Article  PubMed  CAS  Google Scholar 

  • Surwit EA, Manning MR, Aristizabal SA, Oleson JR, Cetas TC (1983) Interstitial thermoradiotherap in recurrent gynecologic malignancies. Gynecol Oncol 15: 95 – 102

    Article  PubMed  CAS  Google Scholar 

  • Touboul E, Lefranc JP, Blondon J, et al. (1992) Preoperative radiation therapy and surgery in the treatment of “bulky” squamous cell carcinoma of the uterine cervix (stages lb, Ha and lib) operable tumors. Radiother Oncol 24: 32 – 40

    Article  PubMed  CAS  Google Scholar 

  • Turner PF (1993) Recent developments using the BSD-2000 system. In: Issels RD, Wilmanns H (eds) Abstracts of the Conference on Hyperthermia in Clinical Oncology, October 25–27, 1993, Munich, p 40 Vaupel P (1990) Oxygenation of human tumors. Strahlenther Onkol 166: 377 – 386

    Google Scholar 

  • Vernon CC (1992) Application of focused ultrasound for local hyperthermia. Strahlenther Onkol 168: 653–656

    Google Scholar 

  • Vora NL, Luk KH (1993) Interstitial thermoradiotherapy for pelvic tumors: the City of Hope Experience. In: Seegenschmiedt MH, Sauer R (eds) Interstitial and intracavitary thermoradiotherapy. Springer, Berlin Heidelberg New York, pp 257 – 264

    Google Scholar 

  • Westermark F (1898) Uber die Behandlung des ulcerie-renden Cervixcarcinoms mittels konstanter Warme. Z Gynakol 49: 1335 – 1339

    Google Scholar 

  • Wust P, Nadobny J, Seebass M, Bohm M, Felix R (1992) Concepts for further improvement of RF-hyperthermia. Strahlenther Onkol 168: 657 – 659

    Google Scholar 

  • Zee van der J, Rhoon van GC, Koper PC, Treurniet- Donker AD, Wijnmaalen AJ (1991) First clinical experience with deep regional hyperthermia. Strahlenther Onkol 167: 349

    Google Scholar 

  • Zee van der J, Gonzales-Gonzales D, Putten van WLJ, et al. (1993) Hyperthermia combined with radio-therapy in deep seated tumours: a phase III trial. In: Issels RD, Wilmanns H (eds) Abstracts of the Conference on Hyperthermia in Clinical Oncology, October 25–27, 1993, Munich, p 41

    Google Scholar 

  • Zimmermann M, Schorcht J, Andree W (1993) Theoretical and experimental investigations of a newly developed intracavitary applicator system for radiothermotherapy of gynaecological tumours. Int J Hyperthermia 9: 463 – 477

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Klinik und Poliklinik für Strahlentherapie, Universitätsklinikum Carl Gustav Carus der TU Dresden, Fetscherstraße 74, D-01307, Dresden, Germany

    Johannes Schorcht MD

  2. Department of Radiation Oncology, University of Erlangen-Nürnberg, Universitätsstraße 27, D-91054, Erlangen, Germany

    M. Heinrich Seegenschmiedt MD

  3. Isotopen-Technik Dr. Sauerwein GmbH, Bergische Straße 16, D-42781, Han, Germany

    Michael Zimmermann PhD

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  1. Johannes Schorcht MD
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  2. M. Heinrich Seegenschmiedt MD
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  3. Michael Zimmermann PhD
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© 1996 Springer-Verlag Berlin Heidelberg

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Schorcht, J., Seegenschmiedt, M.H., Zimmermann, M. (1996). Thermoradiotherapy of Uterine Carcinoma. In: Thermoradiotherapy and Thermochemotherapy. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60938-1_10

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  • DOI: https://doi.org/10.1007/978-3-642-60938-1_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64613-3

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