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Mexoryl SX Protects Against Photoimmunosuppression

  • A. Guéniche
  • A. Fourtanier

Abstract

Exposure of humans to solar radiation seems to be the major carcinogenic agent in the etiology of human skin cancers, at least for basal and squamous cell carcinoma [1, 2]. The biological effects of ultraviolet (UV) components of sunlight that could be involved in this tumoral development include DNA damage and epidermal hyperplasia (for review see [3]). moreover, there is increasing evidence that UV-induced immunomodulatory effects may be important in the development of skin cancer in humans [4]. This immunosuppression can be detected by impaired generation of contact hypersensitivity (CHS) reactions to haptens in both humans [4] and laboratory rodents [5] and decreased reactivity against highly antigenic tumors in mice [6].

Keywords

Dorsal Skin Pyrimidine Dimer Contact Hypersensitivity Urocanic Acid Sunscreen Protection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • A. Guéniche
  • A. Fourtanier

There are no affiliations available

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