Mexoryl SX Protects Against Photoimmunosuppression

  • A. Guéniche
  • A. Fourtanier


Exposure of humans to solar radiation seems to be the major carcinogenic agent in the etiology of human skin cancers, at least for basal and squamous cell carcinoma [1, 2]. The biological effects of ultraviolet (UV) components of sunlight that could be involved in this tumoral development include DNA damage and epidermal hyperplasia (for review see [3]). moreover, there is increasing evidence that UV-induced immunomodulatory effects may be important in the development of skin cancer in humans [4]. This immunosuppression can be detected by impaired generation of contact hypersensitivity (CHS) reactions to haptens in both humans [4] and laboratory rodents [5] and decreased reactivity against highly antigenic tumors in mice [6].


Dorsal Skin Pyrimidine Dimer Contact Hypersensitivity Urocanic Acid Sunscreen Protection 
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© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • A. Guéniche
  • A. Fourtanier

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