Abstract
More than ten standard equations describing physiological dependencies of blood oxygen and acid-base status were combined with the TANH equation. to model the haemoglobin oxygen-binding curve in a computer programme called the Oxygen Status Algorithm. The programme takes measured quantities from blood gas analysers and multi-wavelength spectrophotometers together with a few user-supplied values to calculate a number of derived quantities. The resulting comprehensive blood gas analysis contains almost 30 values, which may be combined, displayed and interpreted with the aid of the programme. It is possible to test the effects of therapeutic measures using ”what if“ functions, reversing several of the calculations. On-line versions are being developed for several commercial analysers allowing easy collection of data. A new interface based on the Windows environment is discussed that makes almost exclusive use of graphical solutions for presentation of the results and interaction with the user.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Siggaard-Andersen O, Wimberley PD, Gøthgen I H, Siggaard-Andersen M (1984) A mathematical model of the hemoglobin-oxygen dissociation curve of human blood and of the oxygen partial pressure as a function of temperature. Clin Chem 30: 1646 – 1651
Siggaard-Andersen O, Siggaard-Andersen M, Fogh-Andersen N (1993) The TAN H equation modified for the hemoglobin, oxygen and carbon monoxide equilibrium. Scand J Clin Lab Invest 53 [Suppl 214]: 113–119
Siggaard-Andersen O, Siggaard-Andersen M (1990) The oxygen status algorithm: a computer program for calculating and displaying pH and blood gas data. Scand J Clin Lab Invest 50 [Suppl 203]: 29 – 45
Siggaard-Andersen M, Siggaard-Andersen O (1995) Oxygen status algorithm, version 3, with some applications. Acta Anaesth Scand 39 [Suppl 107]: 13–20
Siggaard-Andersen O (1977) The Van Slvke equation. Scand J Clin Lab Invest Suppl 146: 15 – 20
Siggaard-Andersen O, Gøthgen IH, Wimberley PD, Fogh-Andersen N (1990) The oxygen status of the arterial blood revised: relevant oxygen parameters for monitoring the arterial oxygen availablility. Scand J Clin Lab invest 50 [Suppl 203]: 17–28
Siggaard-Andersen O, Wimberley PD, Fogh-Andersen N, Gøthgen III (1988) Measured and derived quantities with modern pH and blood gas equipment: calculation algorithms with 54 equations. Scand J Clin Lab Invest [Suppl 189]: 7 – 15
Siggaard-Andersen O (1979) Hydrogen ions and blood gases. In: Brown SS, Mitchell FL, Young DS (eds) Chemical diagnosis of disease. Elsevier, Amsterdam, pp 181 – 245
Siggaard-Andersen 0 (1980) Determination and presentation of acid-base data. Contr Nephrol 21: 128 – 136
Siggaard-Andersen O (1971) An acid-base chart for arterial blood with normal and pathophysiological reference areas. Scand J Clin Lab Invest 27: 239 – 245
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Springer-Verlag Berlin · Heidelberg
About this paper
Cite this paper
Siggaard-Andersen, M. (1997). Computer-Assisted Evaluation of Oxygen and Acid—Base Status of the Blood. In: List, W.F., Müller, M.M., McQueen, M.J. (eds) Advances in Critical Care Testing. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60735-6_27
Download citation
DOI: https://doi.org/10.1007/978-3-642-60735-6_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-62590-2
Online ISBN: 978-3-642-60735-6
eBook Packages: Springer Book Archive