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Quantifying Lung Injury in ARDS

  • Conference paper
Acute Lung Injury

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 30))

Abstract

Normal water homeostasis in the lung is based on a balance among the so-called “Starling” forces: a vascular-to-extravascular hydrostatic pressure gradient, a similar but directionally opposite oncotic pressure gradient, and the “leakiness” or “permeability” of the alveolo-capillary endothelial membrane to protein [1,2]. This paradigm leads to a natural and clinically relevant distinction: Pulmonary edema can be either “cardiogenic”(i.e. due to increased hydrostatic pressures) or “non-cardiogenic” (i.e. due to increased vascular permeability). The prototypical example of non-cardiogenic pulmonary edema is the acute respiratory distress syndrome (ARDS).

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Authors
  1. D. P. Schuster
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Editors and Affiliations

  1. Pulmonary and Critical Care, St. Paul Ramsey Medical Center, 640 Jackson Street, St. Paul, 55101, MN, USA

    John J. Marini

  2. Anaesthesia and Critical Care, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK

    Timothy W. Evans

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© 1998 Springer-Verlag Berlin Heidelberg

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Schuster, D.P. (1998). Quantifying Lung Injury in ARDS. In: Marini, J.J., Evans, T.W. (eds) Acute Lung Injury. Update in Intensive Care and Emergency Medicine, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60733-2_12

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  • DOI: https://doi.org/10.1007/978-3-642-60733-2_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64532-7

  • Online ISBN: 978-3-642-60733-2

  • eBook Packages: Springer Book Archive

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