Splanchnic Blood Flow
The hepatosplanchnic region is functionally and metabolically a very active organ system. In this chapter, the expression “splanchnic” is used interchangeably with “hepatosplanchnic”, and includes the liver and the organs drained by the portal circulation (the gut, the pancreas, and the spleen). Under normal conditions, metabolism of the splanchnic region represents roughly 20–35% of whole body energy expenditure and it receives similar fraction of whole body blood flow [1–4].
KeywordsPermeability Dopamine Adenosine Pancreatitis Angiotensin
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- Bruns FJ, Fraley DS, Haigh J, Márquez JM, Martin DJ, Matuschak GM, Snyder JV (1987) Control of organ blood flow. In: Snyder JV, Pinsky MR (eds) Oxygen transport in the critically ill. Year Book Medical Publishers, Ine, Chicago, pp 87–124.Google Scholar
- Richardson PDI, Withrington PG (1981) Liver blood flow. Intrinsic and nervous control of liver blood flow. Gastroenterology 81:159–173.Google Scholar
- Matuschak GM (1995) Oxidative stress and oxygen-dependent cytokine production. In: Vincent J-L (ed) Yearbook of intensive care medicine. B Springer-Verlag, Germany.Google Scholar
- Fiddian-Green RG, Amelin PM, Herrmann JB, Arous E, Cutler BS, Schiedler M, et al. (1986) Prediction of the development of sigmoid ischemia on the day of aortic operations. Indirect measurements of intramural pH in the colon. Archives of Surgery 121:654–660.Google Scholar
- Gutierrez G, Palizas F, Doglio G, Wainsztein N, Gallesio A, Pacin J, Dubin A, Schiavi E, Jorge M, Pusajo J, Klein F, San Roman E, Dorfman B, Shottlender J, Giniger R (1992) Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patients. Lancet 339:195–199.PubMedCrossRefGoogle Scholar
- Deitch EA (1992) Multiple organ failure. Pathophysiology and potential future therapy. Annals of Surgery 216:117–134.Google Scholar
- Greenway CV, Oshiro G (1972) Comparison of the effects of hepatic nerve stimulation on arterial flow, distribution of arterial and portal flows and the blood content in the livers of anaesthetized cats and dogs. Journal of Physiology (London) 227:487–501.Google Scholar
- Parviainen I, Rantala A, Ruokonen E, Takala J (1995) Failure of enalaprilat to reduce blood pressure in hypertensive cardiac surgery patients. Critical Care Medicine 23 (Suppl): A140.Google Scholar