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Genetic Divergence Among the Group B Coxsackieviruses

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The Coxsackie B Viruses

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 223))

Abstract

Six serotypes comprise the group B coxsackieviruses (CVB 1-6) (Melnick 1996). Similar to other members of the family Picornaviridae, the CVB genome is a single stranded, messenger sense, polyadenylated RNA molecule (Rueckert 1996). Analysis of the genomes from the fully sequenced CVB (CVB1, 3, 4, and 5) (Table 1) further documents their relationship to the Picornaviridae by demonstrating that they are organized into a 5’ nontranslated region, a protein coding region containing a single open reading frame, a 3’ nontranslated region and a terminal polyA tail.

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Author information

Authors and Affiliations

  1. Joint Division of Pediatric Infectious Diseases, Departments of Pediatrics, Creighton University and University of Nebraska Medical Center, Creighton University, 2500 California Plaza, Criss II Rm 409, Omaha, Nebraska, 68178, USA

    J. R. Romero

  2. Department of Medical Microbiology and Immunology, Creighton University, 2500 California Plaza, Criss II Rm 409, Omaha, Nebraska, 68178, USA

    J. R. Romero

  3. Genetic Sequence Analysis Facility, University of Nebraska Medical Center, 600 South 42nd Street, Omaha, Nebraska, 68198, USA

    C. Price

  4. Department of Pathology and Microbiology, University of Nebraska Medical Center, 600 South 42nd Street, Omaha, Nebraska, 68198, USA

    J. R. Romero, C. Price & J. J. Dunn

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  1. J. R. Romero
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  2. C. Price
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  3. J. J. Dunn
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Editor information

Editors and Affiliations

  1. Department of Pathology and Microbiology, University of Nebraska Medical Center, 600 South 42nd Street, Omaha, NE, 69198-6495, USA

    Steven Tracy Ph.D. (Professor) & Nora M. Chapman Ph.D. (Assistant Professor) (Professor) &  (Assistant Professor)

  2. National Center for Infectious Diseases, Centers for Disease Control and Prevention, Clifton Road, Atlanta, GA, 30333, USA

    Brian W. J. Mahy Ph.D., Sc.D. (Director of Viral and Rickettsial Diseases) (Director of Viral and Rickettsial Diseases)

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© 1997 Springer-Verlag Berlin Heidelberg

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Romero, J.R., Price, C., Dunn, J.J. (1997). Genetic Divergence Among the Group B Coxsackieviruses. In: Tracy, S., Chapman, N.M., Mahy, B.W.J. (eds) The Coxsackie B Viruses. Current Topics in Microbiology and Immunology, vol 223. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60687-8_6

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  • DOI: https://doi.org/10.1007/978-3-642-60687-8_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64507-5

  • Online ISBN: 978-3-642-60687-8

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