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Health Effects Associated With Algal Toxins From Seafood

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Applied Toxicology: Approaches Through Basic Science

Part of the book series: Archives of Toxicology ((TOXICOLOGY,volume 19))

Abstract

There are several different types of marine algal toxins which find their way into seafood. In Europe, consumption of mussels infected with toxin producing algae may lead to primarily two types of poisonings, the paralytic shellfish poisoning (PSP) and the diarrhetic shellfish poisoning (DSP). In many countries surveillance programs are in operation in order to reduce the number of intoxications as far as possible. Furthermore, quarantine levels are established to prevent marketing of mussels presenting a health threat to consumers.

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References

  • Aonuma S, Ushijima T, Nakayasu M, Shima H, Suigmura T, Nagao M (1991) Mutation induction by okadaic acid, a protein phosphatase inhibitor in CHL cells, but not in S. typhimurium. Mutat Res 250:375–381.

    PubMed  CAS  Google Scholar 

  • Cohen P (1989) The structure and regulation of protein phosphatases. Annu Rev Biochem 58: 453–508.

    Article  PubMed  CAS  Google Scholar 

  • Cohen P, Cohen PTW (1989) Protein phosphatases come of age. J Biol Chem 264: 21453–21438.

    Google Scholar 

  • Cohen P, Holmes CFB, Tsukitani Y (1990) Okadaic acid: a new probe for the study of cellular regulation. Trends Biochem Sci, March: 98–102.

    Google Scholar 

  • Dho S, Stewart K, Lu D, Grinstein S, Buchwald M, Auerbach W, Foskett JK (1990) Phosphatase inhibition increases tight junctional permeability in cultured human intestinal epithelial cells. J Cell Biol 111: 410A.

    Google Scholar 

  • Fujiki H, Suganuma M (1993) Tumor promotion by inhibitors of protein phosphatases 1 and 2A: The okadaic acid class of compounds. Adv Cancer Res 61:143–194.

    Article  PubMed  CAS  Google Scholar 

  • Hamano Y, Kinoshita Y, Yasumoto T (1985) Suckling mice assay for diarrhetic shellfish toxins. In: Anderson DM, White AW, Baden DG (eds) Toxic Dinoflagellates. Elsevier, New York, pp 383–388.

    Google Scholar 

  • Haystead TAJ, Sim ATR, Carling D, Honnor RC, Tsukitani Y, Cohen P, Hardie DG (1989) Effects of the tumor promoter okadaic acid on intracellular protein phosphorylation and metabolism. Nature 337: 78–81.

    Article  PubMed  CAS  Google Scholar 

  • Hughes JM, Merson MH (1976) Fish and shellfish poisoning. New Engl J Med 295: 1117–1120.

    Article  PubMed  CAS  Google Scholar 

  • Kao CY (1993) Paralytic shellfish poisoning. In: Falconer IR (ed) Algal Toxins in Seafood and Drinking Water. Academic Press, London, pp 75–86.

    Google Scholar 

  • McFarren EF, Schafer ML, Campbell JE, Lewis KH, Jensen ET, Schantz EJ (1960) Public health significance of paralytic shellfish poison. Adv Food Sci 10:135–179.

    CAS  Google Scholar 

  • Meyer KF (1953) Food poisoning. New England J Med 248: 843–852.

    Article  Google Scholar 

  • Oshima Y, Sugino T, Yasumoto T (1989) Latest advances in HPLC analysis of paralytic shellfish toxins. In: Natori S, Hashimoto K, Ueno Y (eds) Myco toxins and Phycotoxins, Elsevier, Amsterdam, pp 319–326.

    Google Scholar 

  • Prakash A, Medcof JC, Tennant AD (1971) Paralytic shellfish poisoning in Eastern Canada. Bull Fish Res Board Can 117:1–88.

    Google Scholar 

  • Rosales-Loessener F, De Porras E, Dix MW (1989) Toxic shellfish poisoning in Guatemala. In: Okaichi T, Anderson DM, Nemoto T (eds) Red Tides: Biology, Environmental Science and Toxicology. Elsevier, New York, pp. 113–116.

    Google Scholar 

  • Suganuma M, Fujiki H, Suguri H, Yoshizawa S, Hirota M, Nakayasu M, Ojika M, Wakamatsu K, Yamada K, Sugimura T (1988) Okadaic acid: an additional non- phorbol-12-tetradecanoate-13 acetate tumor promoter. Proc Natl Acad Sci U.S.A. 85: 1768–1771.

    Article  PubMed  CAS  Google Scholar 

  • Suganuma M, Tatematsu M, Yatsunami J, Yoshizawa S, Okabe S, Uemura D, Fujiki H (1992) An alternative theory of tissue specificity by tumor promotion of okadaic acid in glandular stomach of SD rats. Carcinogenesis 13: 1841–1845.

    Article  PubMed  CAS  Google Scholar 

  • Tachibana K, Scheuer PJ, Tsukitani Y, Kikuchi H, van Engen D, Clardy J, Gopichand Y, Schmitz FJ (1981) Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria. J Am Chem Soc 103: 2469–2471.

    Article  CAS  Google Scholar 

  • Takemoto T (1978) Isolation and structural identification of naturally occurring exitatory amino acids. In: McGeer EG, Olney JW, McGeer PL (eds) Kainic acid as a tool in neurobiology. Raven Press, New York, pp 1–15.

    Google Scholar 

  • Tennant AD, Naubert J, Corbeil HE (1955) An out-break of paralytic shellfish poisoning. J Can Med Assoc 72: 436–439.

    CAS  Google Scholar 

  • Terao K, Ito E, Yanagi T, Yasumoto T (1986) Histopathological studies on experimental marine toxin poisoning. I. Ultrastructural changes in the small intestine and liver of suckling mice induced by dinophysistoxin-1 and pectenotoxin-1. Toxicon 24:1141–1151.

    Article  PubMed  CAS  Google Scholar 

  • Terao K, Ito E, Oarada M, Murata M, Yasumoto T (1990) Histopathological studies on experimental marine toxin poisoning - 5. The effects in mice of yessotoxin isolated from Patinopecten yessoensis and of a desulfated derivative. Toxicon 28: 1095–1104.

    CAS  Google Scholar 

  • Todd ECD (1993) Domoic acid and amnesic shellfish poisoning - A review. J Food Protec 56: 69–83.

    CAS  Google Scholar 

  • Wiberg GS, Stephenson NR (1960) Toxicologic studies on paralytic shellfish poison. Toxicol Appl Pharmacol 2: 607–615.

    Article  PubMed  CAS  Google Scholar 

  • WHO (1984) Aquatic (Marine and Freshwater) Biotoxins. Environmental Health Criteria 37. International Programme on Chemical Safety, World Health Organization, Geneva.

    Google Scholar 

  • Yamashita K, Yasuda H, Pines J, Yasumoto T, Nishitani H, Ohtsubo M, Hunter T, Sugimura T, Nishimoto T (1990) Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc 2/H1 kinase and transiently induces a premature mitosis-like state in BHK21 cells. EMBO J 9:4331–4338.

    PubMed  CAS  Google Scholar 

  • Yasumoto T, Murata M (1993) Marine toxins. Chem Rev 93: 1897–1909.

    Article  CAS  Google Scholar 

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© 1997 Springer-Verlag Berlin Heidelberg

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Aune, T. (1997). Health Effects Associated With Algal Toxins From Seafood. In: Seiler, J.P., Vilanova, E. (eds) Applied Toxicology: Approaches Through Basic Science. Archives of Toxicology, vol 19. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60682-3_37

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  • DOI: https://doi.org/10.1007/978-3-642-60682-3_37

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64505-1

  • Online ISBN: 978-3-642-60682-3

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