Advertisement

Direct Pancreatic Function Tests in the Diagnosis and Staging of Chronic Pancreatitis

  • L. Gullo
Conference paper

Abstract

Ten years ago at the Symposium on Diagnostic Procedures in Pancreatic Diseases [1], I spoke in detail about direct pancreatic function tests and illustrated their diagnostic superiority over other methods. I then concluded by expressing the hope that a simple, noninvasive, and highly sensitive pancreatic function test would be developed in the near future, so that we could abandon duodenal intubation. Unfortunately, this has not occurred, and the direct tests are still the best means of evaluating pancreatic function. Because they are invasive and time-consuming, but also because several sophisticated imaging techniques have become available, they are performed infrequently. Nonetheless, these tests remain, without a doubt, the best means of defining the diagnosis and stage of chronic pancreatitis.

Keywords

Chronic Pancreatitis Pancreatic Function Enzyme Secretion Clinical Onset Exocrine Pancreatic Insufficiency 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Gullo L (1986) Pancreatic function test by means of duodenal intubation. In: P. Malfertheiner and H. Ditschuneit, eds. Diagnostic procedures in pancreatic disease. Springer-Verlag, Berlin Heidelberg, 201–207Google Scholar
  2. 2.
    Wormsley KG (1972) Pancreatic function tests. Clin Gastroenterol 1: 27–51Google Scholar
  3. 3.
    Gullo L, Costa PL, Fontana G, Labò G (1976) Investigation of exocrine pancreatic function by continuous infusion of caerulein and secretin in normal subjects and in chronic pancreatitis. Digestion 14: 97–107PubMedCrossRefGoogle Scholar
  4. 4.
    Gullo L, Costa PL, Labò G (1978) A comparison between injection and infusion of pancreatic stimulants in the diagnosis of exocrine pancreatic insufficiency. Digestion 18: 64–69PubMedCrossRefGoogle Scholar
  5. 5.
    Gullo L (1986) Direct pancreatic function test (duodenal intubation) in the diagnosis of chronic pancreatitis. Gastroenterology 90: 799–800PubMedGoogle Scholar
  6. 6.
    Burton P, Evans DG, Harper AA, Howat HT, Oleesky S, Scott JE, Varley H (1960) A test of pancreatic function in man based on the analysis of duodenal contents after administration of secretin and pancreozymin. Gut 1: 111–118PubMedCrossRefGoogle Scholar
  7. 7.
    Ammann RW, Akovbiantz A, Lardiader F, Schueler G (1984) Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients. Gastroenterology 86: 820–828PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • L. Gullo

There are no affiliations available

Personalised recommendations