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Clinical Value of Multifactorial Classification in the Prognostic Evaluation of Acute Pancreatitis

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Diagnostic Procedures in Pancreatic Disease

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Abstract

Acute pancreatitis (AP) presents a broad clinical spectrum ranging from a mild self-limiting disease to a potentially fatal illness with multiple organ failure [1–4]. The development of pancreatic necrosis in patients with AP results in an increase in clinical severity and in mortality risk compared to acute edematous/ interstitial pancreatitis [5]. The terms severe AP [6] and necrotizing AP [7] are broadly synonymous because the necrotic destruction of pancreatic parenchyma is the major determinant of the severity of the disease. Despite improvements in diagnosis and treatment, necrotizing AP is still associated with a high mortality rate. Several factors influence the clinical course and final outcome of the disease [3, 8–9]: the presence of systemic complications, the extent of intra-pancreatic and extrapancreatic necrosis, the infection of necrosis, and/or fluid collections.

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Authors
  1. G. Uomo
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  2. G. Manes
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  3. P. G. Rabitti
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Editor information

Editors and Affiliations

  1. Klinik für Gastroenterologie, Hepatologie und Infektiologie, Otto-von-Guericke-Universität, Leipziger Straße 44, D-39120, Magdeburg, Germany

    P. Malfertheiner  & J. E. Domínguez-Muñoz  & 

  2. Otto-von-Guericke-Universität, Leipziger Straße 44, D-39120, Magdeburg, Germany

    H.-U. Schulz (Allgemeinchirurgie) (Allgemeinchirurgie)

  3. Chirurgische Klinik, Otto-von-Guericke-Universität, Leipziger Straße 44, D-39120, Magdeburg, Germany

    H. Lippert

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© 1997 Springer-Verlag Berlin Heidelberg

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Uomo, G., Manes, G., Rabitti, P.G. (1997). Clinical Value of Multifactorial Classification in the Prognostic Evaluation of Acute Pancreatitis. In: Malfertheiner, P., Domínguez-Muñoz, J.E., Schulz, HU., Lippert, H. (eds) Diagnostic Procedures in Pancreatic Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60580-2_13

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  • DOI: https://doi.org/10.1007/978-3-642-60580-2_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64464-1

  • Online ISBN: 978-3-642-60580-2

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