Peliosis Hepatis, Rodents

  • Peter Bannasch
  • Klaus Wayss
  • Heide Zerban
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


Macroscopically, peliosis hepatis is best visible at the surface of the liver. The lesion is seen as blood-filled, thin-walled cavities projecting above the liver surface (Fig. 127). The blood-filled spaces stand out clearly as dark areas against the otherwise brown liver tissue. Large peliotic lesions may also be identified at the cut surface. Frequently, however, it is extremely difficult or even impossible to detect peliosis with the naked eye after the animal has died spontaneously under conditions with a weak blood supply to the liver. When the liver is removed from anesthetized animals after laparotomy, peliosis is readily visible only as long as the liver is connected with the blood circulation, but usually becomes invisible when the blood is lost during removal of the organ.


Blood cyst angiectasis phlebectetic or sinusoidal peliosis hepatis parenchymal peliosis hepatis 


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© Springer-Verlag Berlin Heidelberg 1997

Authors and Affiliations

  • Peter Bannasch
  • Klaus Wayss
  • Heide Zerban

There are no affiliations available

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