Abstract
Specific structural chromosome abnormalities are connected with different types of acute myeloid leukemia and have proved to be helpful in establishing the precise diagnosis and the prognosis of disease. For FAB M6 subtype, many karyotype changes have been described and classified as minor and major karyotype abnormalities (MIKA and MAKA) [1]. Here we report the combination of two clonal chromosome changes in a child with M6 AML.
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References
Sakuari M, Sandberg AA (1976). Chromosomes and causation of human cancer and leukemia. XIII. An evaluation of karyotypic findings in erythroleukemic. Cancer 37: 790–804
ISCN (1991). Guidelines for Cancer Cytogenetics. Supplement to an International System for Human Cytogenetic Nomenclature. S. Karger, Basel, 54p.
Santoro A, Carbone P, Caradonna F, Fabbiano F, Mitro S, Caronia F (1993) A New Pericentric inv (8) in Acute Nonlymphocytic Leukemia. Cancer Genet Cytogenet 65: 77–78.
Bertheas MF, Jaubert J, Vasselon C, Reunaud J, Promier G, Le Petit JC, Hagenieijer A, Brizard CP (1989) A complex t(3;8;17) Involving Breakpoint 8pll in a Case of M5 Acute Nonlymphocytic Leukemia with Erythrophagocytosis. Cancer Genet Cytogenet 42: 67–73.
Human Cytogenetics. A Practical Approach. Volume II. Malignancy and Acquired Abnormalities. Second Edition. (Ed. Rooney DE, Czepulkowski BH). Oxford New York Tokyo. Oxford University Press. 293 p
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© 1997 Springer-Verlag Berlin Heidelberg
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Donskaya, S., Andreeva, S., Galantha, A., Sclysarenko, L., Derbenyova, N. (1997). Unusual Karyotype 46,XX,inv(8)(p21q24),del(20)(q11q13) in a Case of Acute Leukemia M6 in a Child. In: Büchner, T., Schellong, G., Ritter, J., Creutzig, U., Hiddemann, W., Wörmann, B. (eds) Acute Leukemias VI. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60377-8_7
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DOI: https://doi.org/10.1007/978-3-642-60377-8_7
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