Abstract
Sensitive techniques for the detection of minimal tumor cell populations are gaining in importance. In hematological disorders they are required for monitoring residual disease after therapy, detection of minimal bone marrow infiltration by malignant lymphoma cells and exclusion of tumor cell contamination after leukapheresis. The applicability of the combination of immunophenotyping and interphase cytogenetics, the FICTION technique, to detection of minimal tumor cell populations is demonstrated in a case of Hodgkin’s disease.
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© 1997 Springer-Verlag Berlin Heidelberg
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Deerberg, J., Rosenwald, A., Weber-Matthiesen, K., Schlegelberger, B. (1997). Detection of Minimal Tumor Cell Populations by FICTION. In: Büchner, T., Schellong, G., Ritter, J., Creutzig, U., Hiddemann, W., Wörmann, B. (eds) Acute Leukemias VI. Haematology and Blood Transfusion / Hämatologie und Bluttransfusion, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60377-8_12
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DOI: https://doi.org/10.1007/978-3-642-60377-8_12
Publisher Name: Springer, Berlin, Heidelberg
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