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The Pathophysiology of Pneumoperitoneum pp 85–98Cite as

Intra-abdominal Pressure, Intracranial Pressure, and Hemodynamics: A Central Nervous System-Regulated Response

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Abstract

Elevation in intra-abdominal pressure (IAP) can be classified as acute or chronic. The development of ascites from liver cirrhosis and portal hypertension, and the presence of retroperitoneal or intraperitoneal tumor masses are some of the more frequent examples of chronic elevation in IAP. The clinical significance of chronic elevations in IAP is related to the underlying pathology. Acute life-threatening changes are rarely observed. In contrast, acute elevations of intra-abdominal pressure have been shown to induce numerous serious hemodynamic, respiratory, and neurohormonal changes. The establishment of pneumoperitoneum in laparoscopic procedures or edema and hemoperitoneum in the abdominal compartment syndrome are the more frequent clinical settings of acute increase in IAP. The number of advanced laparoscopic procedures performed, combined with prolonged patient exposure to carbon dioxide (CO2) has renewed interest in understanding the pathophysiologic effects of increased IAP.

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Authors
  1. R. J. Rosenthal
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  2. R. L. Friedman
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  3. E. H. Phillips
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Editor information

Editors and Affiliations

  1. Department of Surgery, Mount Sinai Medical Center, One L. Gustave Levy Place, New York, NY, 10029-6574, USA

    Raul J. Rosenthal M.D.

  2. The Mount Sinai Hospital, Mount Sinai School of Medicine, One L. Gustave Place, New York, NY, 10029-6574, USA

    Raul J. Rosenthal M.D.

  3. Department of Surgery, Beth Israel Medical Center, 16th Street and 1st. Ave, New York, NY, 10002, USA

    Richard L. Friedman M.D.

  4. Division of Endoscopic Surg., Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA, 90048, USA

    Edward H. Phillips M.D., F.A.C.S.

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© 1998 Springer-Verlag Berlin Heidelberg

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Rosenthal, R.J., Friedman, R.L., Phillips, E.H. (1998). Intra-abdominal Pressure, Intracranial Pressure, and Hemodynamics: A Central Nervous System-Regulated Response. In: Rosenthal, R.J., Friedman, R.L., Phillips, E.H. (eds) The Pathophysiology of Pneumoperitoneum. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60290-0_10

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  • DOI: https://doi.org/10.1007/978-3-642-60290-0_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64339-2

  • Online ISBN: 978-3-642-60290-0

  • eBook Packages: Springer Book Archive

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