Interstitial Laser Therapy of Breast Lesions

  • M. A. Hall-Craggs
Part of the Medical Radiology book series (MEDRAD)


The concept of limited breast-conserving surgery (usually coupled with radiotherapy) in selected patients with breast cancer is now widely accepted, and several prospective randomised trials have shown that neither the disease-free interval nor overall survival are adversely affected in patients treated with breast-conservation surgery as compared with mastectomy (Veronesi et al. 1990; Fisher et al. 1989; Jacobson et al. 1995). However, it is not always associated with a good cosmetic result, and there may be post-therapeutic deformity and scarring. The known safety of breast conservation has prompted research into the application of minimally invasive therapies to breast cancers.


Breast Cancer Laser Fibre Breast Lesion Single Fibre Invasive Therapy 
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  1. Amin Z (1995) Diode lasers. Experimental and clinical review. Laser Med Sci 10:157–163CrossRefGoogle Scholar
  2. Amin Z, Donald JJ, Masters A, et a (1993) Hepatic metastases: interstitial laser photocoagulation with real-time US monitoring and dynamic CT evaluation of treatment. Radiology 187:339–347PubMedGoogle Scholar
  3. Boetes C, Mus RDM, Holland R, et al (1995) Breast tumours: comparative accuracy of MR imaging relative to mammography and US for demonstrating extent. Radiology 197: 743–747PubMedGoogle Scholar
  4. Bown SG (1983) Phototherapy of tumours. World J Surg 7: 700–709PubMedCrossRefGoogle Scholar
  5. Cheong WF, Prahl S, Welch AJ (1990) A review of the optical properties of biological tissues. IEEE J Quantum Electron 26:2166–2185CrossRefGoogle Scholar
  6. Fisher B, Redmond C, Poisson R, et al (1989) Eight year result of a randomized clinical trial comparing total mastectomy and lumpectomy with or without radiation in the treatment of breast cancer. N Engl J Med 320:822–828PubMedCrossRefGoogle Scholar
  7. Hall-Craggs MA, Mumtaz H, Paley M, et al (1996) Dynamic guidance of laser therapy to breast cancer. Radiology 201:177Google Scholar
  8. Harries SA, Amin Z, Smith ME, et al (1994) Interstitial laser photocoagulation as a treatment for breast cancer. Br J Surg 81:1617–1619PubMedCrossRefGoogle Scholar
  9. Jacobson JA, Danforth DN, Cowan KH, et al (1995) Ten-year results of a comparison of conservation with mastectomy in the treatment of stage I and II breast cancer. N Engl J Med 332:907–911PubMedCrossRefGoogle Scholar
  10. Jolesz FA, Blumenfeld SM (1994) Interventional use of magnetic resonance imaging. Magn Reson Q 10:85–96PubMedGoogle Scholar
  11. Mumtaz H, Hall-Craggs MA, Wotherspoon A, et al (1996a) Laser therapy for breast cancer: Magnetic resonance imaging and histopathological correlation. Radiology 200:651–658PubMedGoogle Scholar
  12. Mumtaz H, Hall-Craggs MA, Buonnacorssi G, et al (1996b) Image-guided interstitial laser photocoagulation for fibroadenoma of the breast. Radiology 201:177Google Scholar
  13. Mumtaz H, Hall-Craggs MA, Davidson T, et al (1997) Staging symptomatic primary breast cancer with MR imaging. AJR Am J Roentgenol (in press)Google Scholar
  14. Orel SG, Schnall MD, LiVolsi VA, et al (1994) Suspicious breast lesions: MR imaging with radiologie-pathologie correlation. Radiology 190:485–493PubMedGoogle Scholar
  15. Orel SG, Schnall MD, Powell CM, et al (1995) Staging of suspected breast cancer: effect of MR imaging and MR guided biopsy. Radiology 196:115–122PubMedGoogle Scholar
  16. Stegar AC, Lees WR, Walmsley K, et al (1989) Interstitial laser hyperthermia: a new approach to local destruction of tumours. Br Med J 299:362–365CrossRefGoogle Scholar
  17. Svaasand LO, Boerslid T, Oeveraason M (1985) Thermal and optical properties of living tissue: application to laser-induced hyperthermia. Laser Surg Med 5:589–602CrossRefGoogle Scholar
  18. Veronesi U, Luini A, Beretta E, et al (1990) Conservative treatment of early breast cancer. Long-term results of 1232 cases treated with quadrantectomy, axillary dissection and radiotherapy. Ann Surg 211:250–259PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • M. A. Hall-Craggs
    • 1
  1. 1.MR-Unit, The Middlesex HospitalUniversity College London HospitalsLondonUK

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