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Plant Viral Vectors Based on Tobamoviruses

  • Chapter
Plant Biotechnology

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 240))

Abstract

Viruses are ubiquitous in plants, particularly those associated with agriculture. Plant viruses have a range of features that extend from detrimental to potentially beneficial. Economic loses to agriculture caused by viral infections led to the development of genetic systems that allow manipulation of the virus to manage plant diseases; however, these genetic systems have also led to the development of viruses as beneficial tools, exploiting the ability of the small plus-sense single-stranded RNA viruses that commonly infect higher plants to rapidly amplify virus-related RNAs and produce large amounts of proteins. As early as 1983 Siegel described a strategy for the development of virus-based vectors to express foreign genes in plants, although at that time the technology for manipulation of viruses through cDNA cloning was not yet available, and the issue was controversial (Siegel 1983; van Vloten-Doting 1985). Since that time, in vitro genetic systems have been developed for viruses in different taxonomic groups and several of these have been manipulated to transiently express foreign genes (for review, see Kearney et al. 1995).

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Author information

Authors and Affiliations

  1. Biotechnology Foundation Laboratories, Thomas Jefferson University, Philadelphia, PA, 19107, USA

    V. Yusibov & H. Koprowski

  2. University of Florida, Lake Alfred, FL, 33850, USA

    S. Shivprasad & W. Dawson

  3. Biosource Technologies Inc, Vacaville, CA, 95688, USA

    T. H. Turpen

Authors
  1. V. Yusibov
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  2. S. Shivprasad
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  3. T. H. Turpen
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  4. W. Dawson
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  5. H. Koprowski
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Editor information

Editors and Affiliations

  1. Florist and Nursery Crops Unit, USDA-ARS, USNA, Rm. 238, B-010A, 10300 Baltimore Ave., 20705, Beltsville, MD, USA

    John Hammond Ph.D.

  2. National Biomedical Research Foundation, Georgetown University Medical Center, LR-3, Preclinical Science Building, 3900 Reservoir Road, NW, Washington, DC, 20007, USA

    Peter McGarvey Ph.D.

  3. Biotechnology Foundation Labs., Thomas Jefferson University, Rm. M85, JAH, 1020 Locust Street, 19107, Philadelphia, PA, USA

    Vidaldi Yusibov Ph.D.

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© 2000 Springer-Verlag Berlin Heidelberg

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Yusibov, V., Shivprasad, S., Turpen, T.H., Dawson, W., Koprowski, H. (2000). Plant Viral Vectors Based on Tobamoviruses. In: Hammond, J., McGarvey, P., Yusibov, V. (eds) Plant Biotechnology. Current Topics in Microbiology and Immunology, vol 240. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60234-4_4

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  • DOI: https://doi.org/10.1007/978-3-642-60234-4_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66265-5

  • Online ISBN: 978-3-642-60234-4

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