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Hemodynamic and Cardiac Effects of Nisoldipine in Ischemic Left Ventricular Dysfunction

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Nisoldipine Coat-Core

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Abstract

The use of calcium antagonists in patients with left ventricular dysfunction remains a controversial issue, largely because of evidence of reflex neurohormonal activation and of worsening of congestive heart failure symptoms during their administration [1–5]. However, the negative results observed with some calcium antagonists such as nifedipine or diltiazem [4, 5] are balanced by more promising observations with amlodipine and nisoldipine [6, 7]. In these studies, the calcium antagonists were well tolerated and there was evidence of an improvement in left ventricular ejection fraction or diastolic filling as well as in exercise capacity.

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Authors
  1. Michel Rousseau
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Editors and Affiliations

  1. Division of Cardiology, University of Louvain, Avenue Hippocrate 10/2800, B-1200, Bruxelles, Belgium

    Michel F. Rousseau

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© 1999 Springer-Verlag Berlin Heidelberg

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Rousseau, M. (1999). Hemodynamic and Cardiac Effects of Nisoldipine in Ischemic Left Ventricular Dysfunction. In: Rousseau, M.F. (eds) Nisoldipine Coat-Core. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60220-7_4

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  • DOI: https://doi.org/10.1007/978-3-642-60220-7_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66049-1

  • Online ISBN: 978-3-642-60220-7

  • eBook Packages: Springer Book Archive

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