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Human Macrophage-Derived Chemokine (MDC) is Strongly Expressed Following Activation of both Normal and Malignant Precursor and Mature B Cells

  • Conference paper
Mechanisms of B Cell Neoplasia 1998

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 246))

Abstract

Chemokines are a rapidly expanding group of secreted molecules that selectively control the migration and homing of leukocytes to different sites of inflammation and immune responses [1, 2]. They are believed to perform key functions in secondary lymphoid tissues, where they attract antigen-bearing dendritic cells (DC) [3, 4] and antigen-specific T and B cells, promoting interactions among them and guiding them to appropriate sites [2, 5].

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Author information

Authors and Affiliations

  1. Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA

    P. Ghia, L. M. Nadler & A. A. Cardoso

  2. Istituto per la Ricerca e la Cura del Cancro, Candiolo, Italy

    P. Ghia

  3. Basel Institute for Immunology, Basel, Switzerland

    C. Schaniel & A.G Rolink

Authors
  1. P. Ghia
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  2. C. Schaniel
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  3. L. M. Nadler
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  4. A. A. Cardoso
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Editor information

Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstr. 487, Postfach, CH-4005, Basel, Switzerland

    Fritz Melchers Ph.D.

  2. Laboratory of Genetics Building 37, Room 2B04, National Cancer Institute National Institutes of Health, 37 Convent Drive MSC4255, Bethesda, 20892-4255, MD, USA

    Michael Potter M.D.

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© 1999 Springer-Verlag Berlin Heidelberg

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Ghia, P., Schaniel, C., Rolink, A., Nadler, L.M., Cardoso, A.A. (1999). Human Macrophage-Derived Chemokine (MDC) is Strongly Expressed Following Activation of both Normal and Malignant Precursor and Mature B Cells. In: Melchers, F., Potter, M. (eds) Mechanisms of B Cell Neoplasia 1998. Current Topics in Microbiology and Immunology, vol 246. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60162-0_13

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  • DOI: https://doi.org/10.1007/978-3-642-60162-0_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64283-8

  • Online ISBN: 978-3-642-60162-0

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