Zusammenfassung
Die verschiedenen Aspekte der Pathophysiologie bei Sepsis sind Thema unzähliger Untersuchungen und Veröffentlichungen der letzten Jahre. Obwohl viele dieser Erkenntnisse sicherlich dazu beigetragen haben, das Krankheitsbild der Sepsis besser zu verstehen, haben nur wenige dieser Einsichten in die Pathophysiologie auch neue oder verbesserte Therapieansätze hervorgebracht. So ist das Zusammenspiel und die Bedeutung der verschiedenen Mediatoren des inflammatorischen Systems heute wesentlich besser bekannt. Therapeutische Optionen, dieses auch gezielt zu beeinflussen, liegen, wie unten ausgeführt, jedoch nicht vor. Im folgenden sollen daher nur die pathophysiologischen Aspekte genannt werden, die für die unten genannten therapeutischen Strategien bei Sepsis wichtig sind.
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Meier-Hellmann, A., Brauer, M., Bloos, F. (1999). Sepsis — Pathophysiologie und therapeutische Strategien. In: Refresher Course. Refresher Course, vol 25. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60110-1_10
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DOI: https://doi.org/10.1007/978-3-642-60110-1_10
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