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Klinischer Einsatz und therapeutische Ergebnisse der 3D-geplanten Konformationstherapie des Prostatakarzinoms

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Zusammenfassung

Das Prostatakarzinom stellt eine Hauptindikation bei der Entwicklung 3D-konformer Bestrahlungsverfahren dar. Dabei wird das Zielvolumen in einem dreidimensionalen Patientenmodell definiert und dieses durch einen Bestrahlungsplan mit hoher Konformität bei gleichzeitig steilen Dosisgradienten zu kritischen Risikoorganen erfaßt. Ziel ist eine bessere lokale Kontrolle bei gleichzeitig niedrigeren Nebenwirkungsraten der Strahlenbehandlung und möglicherweise damit auch eine Verbesserung der Über-lebensrate der Patienten. Mit der Möglichkeit der individuellen Anpassung der Dosisverteilung an das zu bestrahlende Zielvolumen bekommen allerdings Aspekte wie Lagerungsgenauigkeit, Organbewegung und Verifikation der Bestrahlungstechnik besondere Bedeutung.

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© 1999 Springer-Verlag Berlin Heidelberg

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Willner, J., Flentje, M. (1999). Klinischer Einsatz und therapeutische Ergebnisse der 3D-geplanten Konformationstherapie des Prostatakarzinoms. In: Prostatakarzinom — urologische und strahlentherapeutische Aspekte. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60064-7_8

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  • DOI: https://doi.org/10.1007/978-3-642-60064-7_8

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  • Print ISBN: 978-3-642-64241-8

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