Sentinel Node Detection and Imaging

  • Mohammad R. S. Keshtgar
  • Wendy A. Waddington
  • Sunil R. Lakhani
  • Peter J. Ell


The concept of the sentinel node represents a major new opportunity to stratify patients for appropriate surgery in cancer. Present enthusiasm is high judging by the many publications in the peer-reviewed literature, and significant attention is being paid to this subject by editorials in the major medical journals [1–3]. The reports are almost uniformly enthusiastic about the potential of this technique, and guidelines have been published for sentinel node detection in carcinoma of the breast. Patients have become aware of the potential of the technology, and it is not uncommon for patients to inform themselves and request the views of individuals or clinical groups on this new staging procedure. Despite all this enthusiasm, however, there are significant differences in practice relating to almost all aspects of the technology involved. Interestingly, in spite of these differences, in general terms groups are reporting encouraging results. It is therefore useful to review the subject of the detection of the sentinel node, introducing readers to the present areas of uncertainty and providing a critical analysis of the data as they have appeared in the literature.


Breast Cancer Sentinel Node Lymphatic Mapping Tumour Thickness Penile Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • Mohammad R. S. Keshtgar
    • 1
  • Wendy A. Waddington
    • 1
  • Sunil R. Lakhani
    • 2
  • Peter J. Ell
    • 1
  1. 1.Institute of Nuclear MedicineRoyal Free and University College Medical School University College LondonLondonUK
  2. 2.Department of HistopathologyRoyal Free and University College Medical School University College LondonLondonUK

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