Abstract
The functional deterioration and failure of joint cartilage in osteoarthritis results from changes in its cells and matrix. Significant changes occur in both synthesis, degradation and structure of matrix molecules of cartilage and other joint tissues during the different phases of development of OA.
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Lohmander, L.S. (1999). The Role of Molecular Markers to Monitor Breakdown and Repair. In: Osteoarthritis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60026-5_15
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