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The Role of Helicobacter pylori Infection in Duodenal and Gastric Ulcer

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Gastroduodenal Disease and Helicobacter pylori

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 241))

Abstract

There now is unequivocal evidence that Helicobacter pylori is the principal etiological factor in duodenal ulcer disease (Rabenek 1991; Veldhuyzen Van Zanten 1994a). H. pylori is also recognized as an important cause of gastric ulcers (Kuipers 1995a). In this review we evaluate the epidemiological evidence that H.pylori is associated with both duodenal and gastric ulcers. We also review current thinking about the pathophysiological mechanisms by which duodenal or gastric ulcers form.

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Author information

Authors and Affiliations

  1. Division of Gastroenterology, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Victoria General Hospital Site, 1278 Tower Road, Halifax, NS, B3H 2Y9, Canada

    S. J. O. Veldhuyzen Van Zanten

  2. School of Microbiology and Immunology, University of New South Wales, Sydney, Australia

    A. Lee

Authors
  1. S. J. O. Veldhuyzen Van Zanten
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  2. A. Lee
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Editor information

Editors and Affiliations

  1. Medical Service (111), Central Texas Veterans Health Care System, Texas A&M University, College of Medicine, 1901 S. First Street, Temple, TX, 76504, USA

    T. Ulf Westblom M.D. (Chief) (Chief)

  2. Department of Pediatrics, Division of Pediatric Gastroenterology, Rainbow Babies and Children Hospital, Case Western Reserve University, 2074 Abington Road, Cleveland, OH, 44106, USA

    Steven J. Czinn M.D.

  3. Institute of Pathology, Case Western Reserve University, Biomedical Research Building, Rm. 919, 10900 Euclid Avenue, Cleveland, OH, 44106-4943, USA

    John G. Nedrud Ph.D. (Associate Professor) (Associate Professor)

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© 1999 Springer-Verlag Berlin Heidelberg

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Van Zanten, S.J.O.V., Lee, A. (1999). The Role of Helicobacter pylori Infection in Duodenal and Gastric Ulcer. In: Westblom, T.U., Czinn, S.J., Nedrud, J.G. (eds) Gastroduodenal Disease and Helicobacter pylori . Current Topics in Microbiology and Immunology, vol 241. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-60013-5_4

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  • DOI: https://doi.org/10.1007/978-3-642-60013-5_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64221-0

  • Online ISBN: 978-3-642-60013-5

  • eBook Packages: Springer Book Archive

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