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Dendritic Cells and Langerhans Cells in the Uptake of Mucosal Antigens

  • G. G. MacPherson
  • L. M. Liu
Chapter
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 236)

Abstract

Dendritic cells (DC) represent heterogenous populations of bone marrow-derived cells that have central roles in the initiation and regulation of immune responses (reviewed in Steinman 1991). The cells under consideration are quite distinct from the follicular DCs found in B-cell areas of lymphoid tissues. It is, however, now clear that there is not a single DC lineage, but that cells with DC properties may arise from at least three lineages and can exist in different states of maturation and activation. The relationships between these lineages and their functional significance in immune responses are far from clear.

Keywords

Dendritic Cell Simian Immunodeficiency Virus Mixed Lymphocyte Reaction Major Histocompatability Complex Dendritic Cell Migration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • G. G. MacPherson
    • 1
  • L. M. Liu
    • 1
    • 2
  1. 1.Sir William Dunn School of PathologyUniveristy of OxfordEngland
  2. 2.Center for Neurologic DiseasesBrigham and Woman’s Hospital, Harvard Medical SchoolBostonUSA

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