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Host Responses to Respiratory Virus Infection and Immunization

  • J. E. CroweJr.
Chapter
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 236)

Abstract

The major viral causes of lower respiratory tract (LRT) disease in humans are respiratory syncytial virus (RSV), parainfluenza viruses (PIV), and the influenza viruses. Despite significant advances in our understanding of the basic virology and molecular biology of these viruses, relatively little is known about the life cycle and spread of these respiratory viruses in vivo. Infection is transmitted primarily by fomites or large-particle aerosols; therefore the initiation site of natural infection is presumed to be the nasopharynx (NP). It is probable that these viruses predominately infect respiratory epithelial cells.

Keywords

Influenza Virus Respiratory Syncytial Virus Respiratory Syncytial Virus Infection Influenza Virus Infection Respiratory Virus Infection 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • J. E. CroweJr.
    • 1
  1. 1.Division of Pediatric Infectious Diseases, Department of PediatricsVanderbilt University Medical SchoolNashvilleUSA

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