Zusammenfassung
Die durch die 1691 GA-Mutation im Faktor-V-Gen bedingte APC-Resistenz (FV:R5O6Q) (Dahlbäck et al. 1993; Bertina et al. 1994; Greengard et al. 1994) gilt derzeit als häufigster hereditärer Risikofaktor für venöse Thromboembolien (VTE) mit einer durchschnittlichen Prävalenz von 22% (range 20-52%) bei Patienten mit primarer VTE (de Stefano et al. 1996; Griffin et al. 1993; Koster et al. 1993; Svensson et al. 1994; Nowak-Göttl et al. 1996; Ehrenforth et al. 1998a).
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Ehrenforth, S. et al. (1999). Koexistenz der Prothrombinvariante 20210 GA bei Patienten mit der Faktor-V: R506Q-Mutation und venöser Thrombophilie. In: Scharrer, I., Schramm, W. (eds) 28. Hämophilie-Symposion Hamburg 1997. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59915-6_9
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