Magnetic Resonance Imaging: Physical Principles to Advanced Applications

  • E. F. Jackson

Abstract

The soft tissue contrast provided by magnetic resonance imaging (MRI) frequently makes it the modality of choice in oncological imaging. The excellent sensitivity of MRI for detecting lesions is due to the dependence of the image contrast and signal-to-noise ratio (SNR) on a wide range of both intrinsic and extrinsic parameters. Intrinsic parameters, which depend on the individual tissue characteristics, include the spin-lattice relaxation time (T1), spin-spin relaxation time (T2), proton density, and the velocity and local chemical environment of the nuclei of interest. Extrinsic parameters that affect image contrast and SNR are those chosen by the person performing the examination. A partial list of such extrinsic parameters includes the particular type of image acquisition sequence, the echo time (TE), repetition time (TR), field-of-view, slice thickness, acquisition bandwidth, various saturation and inversion pulses, and resolution. By appropriate manipulation of the extrinsic parameters, an incredibly wide range of image contrasts can be obtained and can be tailored to provide excellent visualization of anatomy, pathology, and, in some cases, function.

Keywords

Permeability Schizophrenia Lime Neurol Macromolecule 

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© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • E. F. Jackson

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