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Pathology of the Liver Allograft

  • Chapter
Transplantation Pathology

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 92))

Abstract

Liver transplantation is now a well established and widely used treatment for otherwise incurable liver diseases. Steady improvements in donor organ preservation, surgical techniques and immunosuppressive regimens have reduced the rate of complications and allowed many patients to live long after liver transplantation. Likewise, a wide use of diagnostic liver biopsies has increased the confidence of pathologists in interpreting allograft changes at all stages after surgery. In many instances, histological assessment remains the “gold standard” for diagnosis. Due to an increasing number of active liver-transplantation programs and prolonged patient survival, pathologists working in specialised centres as well as those working in referring hospitals may be confronted with liver-allograft biopsies. Therefore, basic knowledge of this topic is now of clinical and academic importance. In the following account, the various pathological changes that may affect liver allografts are reviewed with an emphasis on diagnostic difficulties.

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C. L. Berry

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Portmann, B., Koukoulis, G. (1999). Pathology of the Liver Allograft. In: Berry, C.L. (eds) Transplantation Pathology. Current Topics in Pathology, vol 92. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59877-7_4

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