Abstract
Collagen diseases is a collective term for a group of diseases whose basic pathoanatomic feature is a fibrinoid degeneration (fibrinoid necrosis) of the connective tissues. The pathogenesis of these diseases involves the deposition of immune complexes around blood vessels, resulting in vascular damage. Collagen diseases are characterized clinically by overlap phenomena and immunologically by non-organ-specific autoantibodies, explaining why collagen diseases are classified among the systemic autoimmune disorders. Collagen diseases may be associated with inflammatory joint changes, bone necrosis, and soft-tissue calcifications (Thibièreg-Weissenbach syndrome) which, when accompanied by more or less specific skin changes, overlap the specialties of internal medicine (particularly rheumatology and immunology), clinical radiology, and dermatology and thus should be approached from a synoptic perspective.
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References
Bassett LW, Blocka KLN, Furst DE et al. (1981) Skeletal findings in progressive systemic sclerosis (scleroderma). Am J Roentgenol 136: 1121
Bleifeld CJ, Inglis AE (1974) The hand in systemic lupus erythematodes. J Bone Joint Surg Am 56: 1207
Bohan A, Peter JB (1975) Polymyositis and dermato-myositis. N Engl J Med 292: 344
Braun-Falco O, Plewig G, Wolff HH (1984) Dermatologie und Venerologie. Springer, Berlin Heidelberg New York
Freyschmidt J (1997) Skeletterkrankungen. Klinischradiologische Diagnose und Differentialdiagnose, 2. Aufl. Springer, Berlin Heidelberg New York
Genth E, Mierau R (1993) Jo-l-(Antisynthetase-) Syndrom—verbessern Autoantikörper die Klassifikation von Myositiden? Z Rheumatol 52: 259
Haverbush TJ, Wilde AH, Hawk WA (1974) Osteolysis of the ribs and cervical spine in progressive systemic sclerosis (scleroderma). J Bone Joint Surg Am 56: 637
Le Roy EC, Maricq HR, Kahalch MB (1980) Undifferentiated connective tissue syndroms. Arch Rheum 32:341
Leskinen RH, Skrifvars BV, Laasonen LS et al. (1984) Bone lesions in systemic lupus erythematosus. Radiology 153: 349
Lohr HF, Böcher WO, Hermann E et al. (1993) Interstitial alveolitis as early manifestation of anti-Jo-1-positive polymyositis. Z Rheumatol 52: 307
Pinstein ML, Sebes JI, Leventhal M (1989) Progressive systemic sclerosis (PSS) with cervical cord compression syndrome, osteolysis and bilateral facet arthropathy. Case Report 579. Skeletal Radiol 18: 603
Treher E, Niederhoff A, Gellissen U et al. (1993) Polymyositis and Jo-1-Syndrom. Z Rheumatol 52: 301
Udhoff EJ, Genant HK, Kozin F, Ginsberg M (1977) Mixed connective tissue disease: The spectrum of radiographic manifestations. Radiology 124: 613
Weissmann BN, Rappoport AS, Sosman JL, Schur PH (1978) Radiographic findings in the hands in patients with systemic lupus erythematosus. Radiology 126: 313
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© 1999 Springer-Verlag Berlin Heidelberg
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Freyschmidt, J., Freyschmidt, G. (1999). Collagen Diseases. In: SKIBO-Diseases Disorders Affecting the Skin and Bones. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59867-8_3
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DOI: https://doi.org/10.1007/978-3-642-59867-8_3
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-64159-6
Online ISBN: 978-3-642-59867-8
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