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Radical Nephrectomy

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Carcinoma of the Kidney and Testis, and Rare Urologic Malignancies

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

In 1996, it was estimated that nearly 30600 people would be diagnosed with renal cell carcinoma with approximately 12000 deaths from this disease (Parker et al. 1996). Although this tumor most frequently occurs in patients in their fifth and sixth decades of life, it is not uncommon for it to occur in young, productive, and otherwise healthy adults or even children (Eckschlager and Kodet 1994). This disease clearly constitutes an important health problem in the United States. Currently, over 30% of patients diagnosed with renal cell carcinoma have metastatic disease at presentation. An additional 30%–50% of patients initially diagnosed with local disease will demonstrate locally advanced or even metastatic disease at the time of radical nephrectomy. These statistics, coupled with the lack of an effective adjuvant form of chemotherapy, radiotherapy, or immunotherapy (despite the initial enthusiasm) for renal cell carcinoma, emphasize that this is a surgical disease that needs to be detected and aggressively treated at an early curable stage.

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  1. Department of Urology, University of Southern California, Norris Comprehensive Cancer Center, 1441 Eastlake Ave., Suite 7414, MS #74, Los Angeles, CA, 90033, USA

    J. P. Stein MD (Assistant Professor) & D. G. Skinner MD (Professor and Chairman)

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  1. J. P. Stein MD
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  2. D. G. Skinner MD
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Editors and Affiliations

  1. Department of Radiation Oncology Kenneth Norris Jr. Cancer Hospital and Research Institute, University of Southern California School of Medicine, 1441 Eastlake Avenue, 90033-004, Los Angeles, CA, USA

    Zbigniew Petrovich MD, FACR (Professor of Radiation Oncology and Urology Chairman) (Professor of Radiation Oncology and Urology Chairman)

  2. Department of Urology, Catholic University of Leuven, University Hospitals Gasthuisberg, 49, Herestraat, B-3000, Leuven, Belgium

    Luc Baert MD, PhD (Professor and Chairman) (Professor and Chairman)

  3. Hylda Cohn/American Cancer Society, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor) (Professor of Clinical Oncology, and Professor)

  4. Department of Radiation Oncology, Allegheny University of the Health Sciences Allegheny University Hospitals, Hahnemann Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Professor of Clinical Oncology, and Professor) (Professor of Clinical Oncology, and Professor)

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Stein, J.P., Skinner, D.G. (1999). Radical Nephrectomy. In: Petrovich, Z., Baert, L., Brady, L.W. (eds) Carcinoma of the Kidney and Testis, and Rare Urologic Malignancies. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59839-5_5

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