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Pathology of Renal Cell Carcinoma

  • T. Roskams
  • B. Van Damme
Part of the Medical Radiology book series (MEDRAD)

Abstract

Renal cell carcinomas (RCCs) are clinically, histologically, and genetically a very heterogeneous group of tumors. This heterogeneity is a well-known complicating factor in the diagnosis. The histogenesis of RCC was controversial for a long time, especially in terms of the thesis originally expressed by Virchow and advocated by Grawitz that certain clear cell epithelial renal tumors are derived from ectopic adrenocortical elements (Grawitz 1883). This has led to the terms “hypernephroma,” “Grawitz tumor,” and “hypernephroid renal carcinoma.” Today, preference is given to renal tubular histogenesis, mainly on the basis of animal experiments with carcinogens and observation of prestages and early stages of epithelial renal tumors in human kidneys (Bannasch and Zerban 1990).

Keywords

Renal Cell Carcinoma Papillary Renal Cell Carcinoma Renal Oncocytoma Renal Cell Tumor Clear Cell RCCs 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • T. Roskams
    • 1
  • B. Van Damme
    • 1
  1. 1.Department of PathologyUniversity Hospitals (K.U. Leuven)LeuvenBelgium

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