Skip to main content
SpringerLink
Log in
Book cover

Modern Head and Neck Imaging pp 49–78Cite as

Functional MR Imaging and Auditory Activation

  • Chapter

  • 199 Accesses

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

The processing of sound is one of the most complex sensory functions of the human brain, characterized by extensive modulation of neural signals in the brain stem prior to the ultimate expression of input in the auditory cortex. Processing at the level of the cortex is equally complex, reflecting the capacity of the human animal to decode and encode complex stimuli such as speech. Because of the unique capabilities of the human brain, neurophysiological studies using animals have left us with an incomplete picture of human auditory function. Investigators and clinicians studying hearing are anxious to apply new techniques to the human animal that will allow us to peer even further into the complex workings of the auditory system. Minimally invasive or noninvasive techniques, such as PET, FMRI, and MEG, that allow the study of human auditory function hold great promise and expectations.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bandettini PA, Wong EC, Hinks RS, et al (1992) Time course EPI of human brain function during task activation. Magn Reson Med 25:390–397

    Article  PubMed  CAS  Google Scholar 

  • Bandettini PA, Jesmanowicz A, Wong EC, et al (1993) Processing strategies for time-course data sets in functional MRI of the human brain. Magn Reson Med 30:161–73

    Article  PubMed  CAS  Google Scholar 

  • Bandettini PA, Jesmanowicz A, Van Kylen J, et al (1997) Functional MRI of scanner acoustic noise induced brain activation. Neuroimage 5:S193

    Google Scholar 

  • Bannister LH, Berry MM, Collins P, et al (1995) Gray’s Anatomy, 38th edn. Churchill Livingstone, Edinburgh, pp 1024–1027

    Google Scholar 

  • Baumgartner R, Scarth G, Teichtmeister C, et al (1997) Fuzzy clustering of gradient-echo functional MRI in the human visual cortex. I. Reproducibility. J Magn Reson Imaging 7:1094–1101

    Article  PubMed  CAS  Google Scholar 

  • Belliveau JW, Kennedy DN, McKinstry RC, et al (1991) Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254:716–719

    Article  PubMed  CAS  Google Scholar 

  • Berry I, Demonet JF, Warach S, et al (1995) Activation of association auditory cortex demonstrated with functional MRI. Neuroimage 2:215–219

    Article  PubMed  CAS  Google Scholar 

  • Binder JR, Rao SM, Hammeke TA, et al (1994a) Functional magnetic resonance imaging of human auditory cortex. Ann Neurol 35:662–672

    Article  CAS  Google Scholar 

  • Binder JR, Rao SM, Hammeke TA, et al (1994b) Effects of stimulus rate on signal response during functional magnetic resonance imaging of auditory cortex. Cogn Brain Res 2:31–38

    Article  CAS  Google Scholar 

  • Binder JR, Rao SM, Hammeke TA, et al (1995) Lateralized human brain language systems demonstrated by task subtraction functional magnetic resonance imaging. Arch Neurol 52:593–601

    PubMed  CAS  Google Scholar 

  • Binder JR, Frost J A, Hammeke TA, et al (1996) Function of the left planum temporale in auditory and linguistic processing. Brain 119:1239–1247

    Article  PubMed  Google Scholar 

  • Biswal B, Hyde J S (1997b) Contour-based registration technique to differentiate between task-activated and head motion-induced signal variations in FMRI. Magn Reson Med 38:470–476B

    Google Scholar 

  • Biswal B,. DeYoe EA, Jesmanowicz A (1994) FMRI analysis for aperiodic task activation using non-paramagnetic statistics. Proceedings of the Society of Magnetic Resonance, San Francisco, p 624

    Google Scholar 

  • Biswal B, DeYoe AE, Hyde JS (1996) Reduction of physiological fluctuations in fMRI using digital filters. Magn Reson Med 35:107–113

    Article  PubMed  CAS  Google Scholar 

  • Biswal B, Jesmanowicz A, Hyde JS (1997a) High temporal resolution FMRI. Proceedings of the Fifth ISMRM, Vancouver, p 1629

    Google Scholar 

  • Bowtell RW, Mansfield P (1995) Quiet transverse gradient coils:Lorentz force balanced designs using geometrical similitude. Magn Reson Med 34:494–497

    Article  PubMed  CAS  Google Scholar 

  • Boxerman JL, Hamberg LM, Rosen BR, et al (1995) MR contrast due to intravascular magnetic susceptibility perturbations. Magn Reson Med 34:555–566

    Article  PubMed  CAS  Google Scholar 

  • Brammer MJ, Bullmore ET, Simmons A, et al (1997) Generic brain activation mapping in functional magnetic resonance imaging:a nonparametric approach. Magn Reson Imaging 15:763–770

    Article  PubMed  CAS  Google Scholar 

  • Brugge JF (1991) Neurophysiology of the central auditory and vestibular systems. In:Paparella MM (ed) Otolaryngology, vol 1. Saunders, Philadelphia, pp 281–301

    Google Scholar 

  • Buchel C, Wise RJ, Mummery CJ, et al (1996) Nonlinear regression in parametric activation studies. Neuroimage 4:60–66

    Article  PubMed  CAS  Google Scholar 

  • Celesia GG (1976) Organization of auditory cortical areas in man. Brain 99:403–414

    Article  PubMed  CAS  Google Scholar 

  • Chen W, Novotny EJ, Zhu XH, et al (1993) Localized !H NMR measurement of glucose consumption in the human brain during visual stimulation. Proc Natl Acad Sci USA 90:896–900

    Google Scholar 

  • David AS, Woodruff PW, Howard R, et al (1996) Auditory hallucinations inhibit exogenous activation of auditory association cortex. Neuroreport 22;7:932–936

    Google Scholar 

  • Desmond JE, Sum JM, Wagner AD, et al (1995) Functional MRI measurement of language lateralization in Wada- tested patients. Brain 118:1411–1419

    Article  PubMed  Google Scholar 

  • Detre J A, Williams DS, Leigh JS, et al (1991) Quantitative measurement of tissue perfusion and diffusion. Magn Reson Med 19:266–269

    Article  Google Scholar 

  • Dhankhar A, Wexler BE, Fulbright RK, et al (1997) Functional magnetic resonance imaging assessment of the human brain auditory cortex response to increasing word presentation rates. American Physiological Society, Baltimore, pp 476–481

    Google Scholar 

  • Edelman RR, Siewert B, Darby DG, et al (1994) Qualitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency. Radiology 192:513–520

    PubMed  CAS  Google Scholar 

  • Forman SD, Cohen JD, Fitzgerald M, et al (1995) Improved assessment of significant activation in functional magnetic resonance imaging (fMRI):use of a cluster-size threshold. Magn Reson Med 33:636–647

    Article  PubMed  CAS  Google Scholar 

  • Frahm J, Kruger G, Merboldt KD, et al (1996) Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man. J Magn Reson Med 35:143–148

    Article  CAS  Google Scholar 

  • Fransson P, Kruger G, Merboldt KD, et al (1997) A comparative FLASH and EPI study of repetitive and sustained visual activation. NMR Biomed 10:204–207

    Article  PubMed  CAS  Google Scholar 

  • Friston KJ, Williams S, Howard R, et al (1996) Movement- related effects in fMRI time-series. Magn Reson Med 35:346–355

    Article  PubMed  CAS  Google Scholar 

  • Grady CL Van Meter JW Maisog JM et al (1997) Attention- related modulation of activity in primary and secondary auditory cortex Neuroreport. 8:2511–16

    CAS  Google Scholar 

  • Greenberg S 1988 The ear as a speech analyzer. J Phon 16:139–149

    Google Scholar 

  • Hinke RM, Hu X, Stillman AE, et al (1993) Functional magnetic resonance imaging of Broca’s area during internal speech Neuroreport 4:675–678

    Google Scholar 

  • Kim SG (1995) Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique:application to functional mapping. Magn Reson Med 34:293–301

    Article  PubMed  CAS  Google Scholar 

  • Kim SG, Tsekos NV, Ashe J (1997) Multi-slice perfusion-based functional MRI using the FAIR technique:comparison of CBF and BOLD effects. NMR Biomed 10:191–196

    Article  PubMed  CAS  Google Scholar 

  • Kim T, Ulmer J, Haughton V, et al (1997) The effect ofpostprocessing algorithm on the pattern and intensity of activation in functional MR imaging. Proceedings of the 35th Annual Meeting of the American Society of Neuroradiology, 18–22 May 1997, pl45

    Google Scholar 

  • Knudsen EI, Brainard MS (1995) Creating a unified representation of visual and auditory space in the brain. Annu Rev Neurosci 18:19–43

    Article  PubMed  CAS  Google Scholar 

  • Kwong KK, Belliveau JW, Chesler DA, et al (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89:5675–5679

    Article  PubMed  CAS  Google Scholar 

  • Kwong KK, Chesler DA, Weisskoff RM, et al (1995). MR perfusion studies with T1-weighted echo planar imaging. Magn Reson Med 34:878–887

    Article  PubMed  CAS  Google Scholar 

  • Langner G (1992) Periodicity coding in the auditory system (review article). Hear Res 60:115–142

    Article  PubMed  CAS  Google Scholar 

  • Lauter JL, Herscovitch P, Formby C, et al (1985) Tonotopic organization in human auditory cortex revealed by positron emission tomography. Hear Res 20:199–205

    Article  PubMed  CAS  Google Scholar 

  • Malonek D, Grinvald A (1996) Interactions between electrical activity and cortical microcirculation revealed by imaging spectroscopy:implications for functional brain mapping. Science 272:551–554

    Article  PubMed  CAS  Google Scholar 

  • Mansfield P, Glover PM, Beaumont J (1998) Sound generation in gradient coil structures for MRI. Magn Reson Med 39:539–550

    Article  PubMed  CAS  Google Scholar 

  • Mansfield P, Glover PM, Beaumont J (1998) Sound generation in gradient coil structures for MRI. Magn Reson Med 39:539–550

    Article  PubMed  CAS  Google Scholar 

  • Masterton RB (1992) Role of the central auditory system in hearing:the new direction. Trends Neuroscil5:280–285

    Google Scholar 

  • Millen SJ, Haughton VM, Yetkin FZ (1995) Functional magnetic resonance imaging of the central auditory pathway following speech and pure-tone stimuli. Laryngoscope 104:1305–1310

    Article  Google Scholar 

  • Moser E, Diemling M, Baumgartner R (1997) Fuzzy clustering of gradient-echo functional MRI in the human visual cortex. II. Quantification. J Magn Reson Imaging 7:1102–1108

    Article  PubMed  CAS  Google Scholar 

  • Musiek FE, Hoffman DW (1990) An introduction to the functional neurochemistry of the auditory system. Ear Hear 11:395–402

    Article  PubMed  CAS  Google Scholar 

  • Newby HA, Popelka GR (1992) What and how we hear. In:Audiology, 6th edn. Prentice-Hall, Englewood Cliffs Nieuwenhuys R (1984) Anatomy of the auditory pathways, with emphasis on the brain stem. Adv Otorhinolaryngol 34:25–38

    Google Scholar 

  • Nieuwenhuys R, Voogd J, van Huijzen C (1988) The human central nervous system, 3rd edn. Springer, Berlin Heidelberg New York, pp 172–179

    Google Scholar 

  • Noll DC, Cohen JD, Meyer CH, et al (1995) MR imaging of cortical activation. J Magn Reson Imaging 5:49–56

    Google Scholar 

  • Northern JL, Downs MP (1991) Hearing in children, 4th edn. Williams & Wilkins, Baltimore

    Google Scholar 

  • Ogawa S, Tank DW Menon R, et al (1992) Intrinsic signal changes accompanying sensory stimulation:functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89:5951–5955

    Article  PubMed  CAS  Google Scholar 

  • Ogawa S, Menon RS, Tank DW, et al (1993) Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. Biophys J 64:803–812

    Article  PubMed  CAS  Google Scholar 

  • Plomp R (1983) The role of modulation in hearing. In:Klinke R, Hartmann R (eds) Hearing - physiological bases and psycho- physics. Springer, Berlin Heidelberg NewYork, pp 270–275

    Google Scholar 

  • Roberts TPL, Poeppel D (1996) Latency of auditory evoked Ml 00 as a function of tone frequency. Neuroreport 7:1138–1140

    Google Scholar 

  • Roland PE (1993) Language. In:Roland PE (ed) Brain activation. Wiley-Liss, New York, pp 158–163

    Google Scholar 

  • Sigalovsky I, Levine RA, Melcher JR, et al (1998) Tinnitus studied using functional magnetic resonance imaging:development of methods. Proceedings of the Twenty-First Midwinter Meeting of the Association for Research in Otolaryngology, p 51

    Google Scholar 

  • Stehling MK, Turner R, Mansfield P (1991) Echo-planar imaging:magnetic resonance imaging in a fraction of a second. Science 254:43–50

    Article  PubMed  CAS  Google Scholar 

  • Strainer JC, Ulmer JL, Yetkin FZ, et al (1997) Functional MR of the primary auditory cortex:an analysis of pure tone activation and tone discrimination. AJNR Am J Neuroradiol 18:601–610

    PubMed  CAS  Google Scholar 

  • Swartz JD, Daniels DL, Harnsberger HR, et al (1996a) Hearing.

    Google Scholar 

  • I. The cochlea. AJNR Am J Neuroradiol 17:1237–1241

    Google Scholar 

  • Swartz JD, Daniels DL, Harnsberger HR, (1996b) Hearing. II. The retrocochlear auditory pathway. AJNR Am J Neuroradiol 17:1479–1481

    CAS  Google Scholar 

  • Talavage TM, Edmister WB (1998) Measuring and reducing the impact of imaging noise on echo-planar functional magnetic resonance imaging (fMRI) of auditory cortex. Abstracts of the Twenty-first Midwinter Research Meeting of the Association for Research in Otolaryngology, no 138

    Google Scholar 

  • Talavage TM, Ledden PJ, Sereno MI, et al (1996) fMRI evidence of tonotopic organization in human auditory cortex. Human Brain Mapping

    Google Scholar 

  • Talavage TM, Ledden PJ, Sereno MI, et al (1997a) Evidence for multiple frequency-selective fields in human auditory cortex obtained by functional magnetic resonance imaging. Abstracts of the Twentieth Midwinter Research Meeting of the Association for Research in Otolaryngology, no 818

    Google Scholar 

  • Talavage TM, Ledden PJ, Sereno MI, et al (1997b) Multiple phase-encoded tonotopic maps in human auditory cortex. Neuroimage 5:S8 Tan SG, Song AW, Wong EC, et al (1997) High resolution FMRI with interleaved EPI. Proceedings of the Fifth ISMRM, Vancouver, p 796, April 12–18, 1997

    Google Scholar 

  • Ulmer JL, Estkowski LD, Yetkin FZ, et al (1996a) Functional MR imaging of the auditory cortex:cortical activation response to acoustic scanner noise. Radiology 201 [Suppl]:373

    Google Scholar 

  • Ulmer JL, Strainer JC, Yetkin FZ, et al (1996b) Functional MR imaging of the auditory cortex:pure tone activation and auditory cortical function. Radiology 201 (P):451

    Google Scholar 

  • Ulmer JL, Akansel G, Yetkin FZ, et al (1997) A functiimaging investigation of language comprehension:a comparison of passive text listening between intelligible and unintelligible languages. Proceedings of the 35th Annual Meeting of the American Society of Neuroradiology, 18–22 May, p 329

    Google Scholar 

  • Ulmer JL, Biswal BB, Yetkin FZ, et al (1998a) Cortical activation response to acoustic echoplanar scanner noise. J Comput Assist Tomogr 21:111–119

    Article  Google Scholar 

  • Ulmer JL, Biswal BB, Mark LP, et al (1998b) Acoustic echoplanar scanner noise and pure tone hearing thresholds:the effects of sequence repetition times and acoustic noise rates. J Comput Assist Tomogr 22:480–486

    Article  CAS  Google Scholar 

  • Ulmer JL, Mark LP, Mathews VP, et al (1998c) Auditory activation and perceptual effects from acoustic echoplanar scanner noise (exhibit). Proceedings of the 36th Annual Meeting of the American Society of Neuroradiology, 17–21 May 1998

    Google Scholar 

  • Ulmer JL, Millen SJ, Mark LP, et al (1998d) Functional magnetic resonance imaging of the primary auditory cortex:a study of activation patterns with varying pure tone intensity levels. Proceedings of the 36th Annual Meeting of the American Society of Neuroradiology, 17–21May 1998

    Google Scholar 

  • Villringer A, Dirnagl U (1995) Coupling of brain activity and cerebral blood flow:basis of functional neuroimaging. Cerebrovasc Brain Metab Rev 7:240–276

    PubMed  CAS  Google Scholar 

  • Williams DS, Detre JA, Leigh JS, et al (1992) Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc Natl Acad Sci USA 89:4220–4226

    Article  CAS  Google Scholar 

  • Wong EC, Buxton RB, Frank LR (1997) Implementation of quantitative perfusion imaging techniques for functional brain mapping using pulsed arterial spin labeling. NMR Biomed 10:237–249

    Article  PubMed  CAS  Google Scholar 

  • Woods RP, Cherry SR, Mazziotta JC (1992) Rapid automated algorithm for aligning and reslicing PET images. J Comput Assist Tomogr 16:620–633

    Article  PubMed  CAS  Google Scholar 

  • Worsley KJ, Poline JB, Vandal AC, et al (1995) Tests for distributed, nonfocal brain activations. Neuroimage 2:183–194

    Article  PubMed  CAS  Google Scholar 

  • Yetkin FZ, Mueller W, Cox RW, et al (1996) Dependence of postoperative neurologic deficit on distance from lesion to eloquent cortex as measured by functional MR imaging. In:Proceedings of the 34th Annual Meeting of the American Society of Neuroradiology, Seattle, p 61, June 21–27

    Google Scholar 

  • Yetkin FZ, Mueller W, Morris G, et al (1997) Activation in FMRI correlated with intraoperative cortical mapping. AJNR Am J Neuroradiol 18:1311–1315

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, 9200 West Wisconsin Avenue, 53226, Milwaukee, WI, USA

    J. L. Ulmer MD, L. P. Mark MD & D. L. Daniels MD

  2. Department of Biophysics, Medical College of Wisconsin, Froedtert Memorial Lutheran, 9200 West Wisconsin Avenue, 53226, Milwaukee, WI, USA

    B. Biswal PhD

Authors
  1. J. L. Ulmer MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. L. P. Mark MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. Biswal PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. L. Daniels MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Radiology The School of Medicine, University of North Carolina at Chapel Hill, 27599-7510, Chapel Hill, NC, USA

    Suresh K. Mukherji MD

  2. Department of Radiology, Academisch Ziekenhuis Vrije Universiteit, 1007 MB, P.O.Box 7057, Amsterdam, The Netherlands

    J. A. Castelijns MD

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Ulmer, J.L., Mark, L.P., Biswal, B., Daniels, D.L. (1999). Functional MR Imaging and Auditory Activation. In: Mukherji, S.K., Castelijns, J.A. (eds) Modern Head and Neck Imaging. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59826-5_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-59826-5_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66344-7

  • Online ISBN: 978-3-642-59826-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation