Induction or Concurrent Chemotherapy and Radiation Therapy for Locally Advanced Non-Small Cell Lung Cancer

  • R. Komaki
  • J. D. Cox
Part of the Medical Radiology book series (MEDRAD)


Thoracic radiation therapy was considered to be the standard care for patients with inoperable non-small cell lung cancer (NSCLC) in the United States for many years. Although the long-term results of such treatment were far from satisfactory (a large number of investigators reported approximately 1 patient of 20 treated survived 5 years), it was the only modality that offered any possibility of cure for patients with unresectable tumors. Over the past few years, combined chemotherapy and thoracic radiation therapy (TRT) have become standard treatment for patients with unresectable NSCLC if they have good performance status and minimal or no weight loss (SHAAKE-KONIG et al. 1992; DILLMAN et al. 1990; LECHEVALIER et al. 1991; SAUSE et al. 1995).


Induction Chemotherapy Radiation Therapy Oncology Group Local Tumor Control Concurrent Chemotherapy Compare Radiation Therapy 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • R. Komaki
    • 1
  • J. D. Cox
    • 2
  1. 1.The University of Texas M.D. Anderson Cancer CenterHoustonUSA
  2. 2.Department of Radiation OncologyThe University of Texas M.D. Anderson Cancer CenterHoustonUSA

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