Abstract
Rupture, abscess formation, and re-encapsulation is the key sequence which underlies the creation of secondary comedones. These can arise only when rupture is partial, and generally not from nodules. Substantial segments of comedonal epithelium must survive the inflammatory storm. Because focal rupture and re-encapsulation may happen once or many times, secondary comedones cannot be placed in such neat categories as primary ones; they are exceedingly variable in size and shape. Some of them may look like closed or open comedones. Secondary comedones can be identified with certainty only by histological examination.
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References
Bouwstra JA, Gooris GS, Dubbelaar FER, Weerheim AM, Ponec M (1998) pH, cholesterol sulfate, and fatty acids affect the stratum corneum lipid organization. J Invest Dermatol Symp Proceedings 3:69–74
Elias PM, Cullander C, Mauro T, Rassner U, Kömüves L, Brown BA, Menon GK (1998) The secretory granular cell: the ourermost granular cell as a specialized secretory cell. J Invest Dermatol Symp Proceedings 3: 80–86
Hou SYE, Mitra AK, White SH, Menon GK, Ghadially R, Elias PM (1991) Membrane structures in normal and essential fatty acid-deficient stratum corneum: characterization by ruthenium tetroxide staining and x-ray diffraction. J Invest Dermatol 96: 215–223
Madison KC, Sando GN, Howard EJ, True CA, Gilbert D, Swartzendruber DC, Wertz PW (1998) Lamellar granule biogenesis: a role for ceramide glucosyltransferase, lysosomal enzyme transport, and the golgi. J Invest Dermatol Symp Proceedings 3: 80–86
Reference
Plewig G, Fulton JE, Kligman AM (1971) Cellular dynamics of comedo formation in acne vulgaris. Arch Dermatol Forsch 242: 12–29
Reference
Leyden JJ, Kligman AM (1972) Hairs in acne comedones. Arch Dermatol 106: 851–853
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© 2000 Springer-Verlag Berlin Heidelberg
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Plewig, G., Kligman, A.M. (2000). Dynamics of Secondary Comedo Formation. In: ACNE and ROSACEA. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59715-2_11
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DOI: https://doi.org/10.1007/978-3-642-59715-2_11
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-66751-3
Online ISBN: 978-3-642-59715-2
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