Genome Paralogy: A New Perspective on the Organization and Origin of the Major Histocompatibility Complex

  • M. Kasahara
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 248)


The coordinated international project to sequence the entire human major histocompatibility complex (MHC) is approaching its end. We will probably see the complete nucleotide sequence of the mouse MHC in the near future. Thus, for the time being, the MHC is likely to remain one of the best characterized genetic regions in the mammalian genome.


Adaptive Immune System Cartilaginous Fish Chromosomal Duplication Paralogous Copy Paralogous Region 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • M. Kasahara
    • 1
  1. 1.Department of Biosystems Science, School of Advanced SciencesGraduate University for Advanced Studies, and Core Research for Evolutionary Science and Technology, JSTHayamaJapan

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