Genes and Centenarians
It has been purported that aging was due to the interaction of many genes, perhaps eight to ten thousand, with weak effects interacting with one another and our internal and external environments. Yet genetic experiments in lower organisms and our own centenarian pedigree data indicate that at least a few genes may exist that exert a powerful influence upon longevity. Experiments C. elegans, Drosophila and yeast show that the manipulation of one or a few different genes can result in the doubling to quintupling of life span. We have found that a sibling of a centenarian has a four to five times greater chance of reaching his/her early nineties compared to the sibling of someone who died his/her early 70s (Hitt 1999).
KeywordsPremature Ovarian Failure Average Life Expectancy Human Longevity Pilot Whale Human Life Span
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