Skip to main content

Skin Lesions of Fibrocytic and Fibrohistiocytic Differentiation: A New Concept and Classification

  • Chapter

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 94))

Abstract

The WHO classification of soft-tissue tumours derives from an article in a fascicle of the AFIP atlas in 1953 by Arthur Purdy Stout [1], the leading specialist on soft-tissue neoplasia at that time, and was later modified several times. Its current version [2] differentiates entities according to their histopathological derivation into 15 different groups, among them fibrous and fibrohistiocytic tumours, and further subdivides both of these according to their biological behaviour into benign, intermediate, and malignant lesions (Table 1). However, there are great difficulties with this classification, for several reasons.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Stout AP (1953) Tumors of the soft tissue. In: Atlas of tumor pathology. Fasc. 5, Sect. II. Armed Forces Institute of Pathology, Washington, DC

    Google Scholar 

  2. Weiss SW (1994) Histological typing of soft tissue tumours. In: Sobin LH (ed) International histological classification of tumours. Fasc. 3, 2nd edn. Springer, Berlin Heidelberg New York

    Google Scholar 

  3. Ackerman AB, Chongchitnant N, Sanchez J, Guo Y, Bennin B, Reichel M, Randall MB (eds) (1997) Histologic diagnosis of inflammatory skin disorders. An algorithmic method based on pattern analysis, 2nd edn. Williams and Wilkins, Baltimores

    Google Scholar 

  4. Ackerman AB, Cavegan BM, Robinson MJ, Abad-Casintahan MFA (eds) (1995) Ackerman’s resolving quandries in dermatology, pathology and dermatopathology. Promethean Medical Press, Philadelphia

    Google Scholar 

  5. Jacobs DS, Edwards WD, Ye RC (1975) Metastatic atypical fibroxanthoma of the skin. Cancer 35:457–463

    Article  PubMed  CAS  Google Scholar 

  6. Enzinger FM, Weiss SW (1995) Soft tissue tumors, 3rd edn. Mosby, St. Louis

    Google Scholar 

  7. CDM Fletcher (1995) Diagnostic pathology of tumors. Churchill Livingstone, Edinburgh

    Google Scholar 

  8. Ackerman AB, DeViragh PA, Chongchitnant N (1993) Neoplasms with follicular differentiation. Lea & Febinger, Philadelphia

    Google Scholar 

  9. Calonje E, Fletcher CDM (1994) Cutaneous fibrohistiocytic tumors: an update. Adv Anatomic Pathol 1:2–15

    Article  Google Scholar 

  10. Zeiger BG, Zeiger B (1998) Dermatofibrome. Ein klinisch-pathologisches Klassifikationsschema. Pathologe 19:412–419

    Article  Google Scholar 

  11. Zeiger BG, Steiner H, Kutzner H, Maier H, Zeiger B (1998) Cellular “neurothekeoma”: an epithelioid variant of dermatofibroma? Histopathology 32:414–422

    Article  Google Scholar 

  12. Zeiger BG, Calonje E, Zeiger B (1999) Myxoid dermatofibroma. Histopathology 34:357–364

    Article  Google Scholar 

  13. Zeiger BG, Sidoroff A, Zeiger B (2000) Combined dermatofibroma: co-existence of two or more variant patterns in a single lesion. Histopathology 36:529–539

    Article  Google Scholar 

  14. Zeiger B, Weinlich G, Steiner H, Zeiger BG, Egarter-Vigl E (1997) Dermal and subcutaneous variants of plexiform fibrohistiocytic tumor. Am J Surg Pathol 21:235–241

    Article  Google Scholar 

  15. Zeiger B, Sidoroff A, Orchard G, Cerio R (1996) Non-Langerhans’ cell histiocytoses - a new unifying concept. Am J Dermatopathol 18:490–504

    Article  Google Scholar 

  16. Zeiger BG, Orchard G, Rudolph P, Zeiger B (1998) Scalloped cell xanthogranuloma. Histopathology 32:368–374

    Article  Google Scholar 

  17. Fletcher CDM (1992) Pleomorphic malignant fibrous histiocytoma: fact or fiction? A critical reappraisal based on 159 tumors diagnosed as pleomorphic sarcoma. Am J Surg Pathol 16:213–228

    Article  PubMed  CAS  Google Scholar 

  18. Zeiger B, Soyer HP (2000) Between Scylla and Charybdis. Mythology in dermatopathology. Dermatopathol: Pract & Concep 6: 348–355

    Google Scholar 

  19. Evans HL (1993) Low-grade fibromyxoid sarcoma. A report of 12 cases. Am J Surg Pathol 17:595–600

    Article  PubMed  CAS  Google Scholar 

  20. Dei Tos A, Seregard S, Calonje E, Chan JKC, Fletcher CDM (1995) Giant cell angiofibroma. A distinctive orbital tumor in adults. Am J Surg Pathol 19:1286–1293

    Article  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2001 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Zelger, B.G., Zelger, B. (2001). Skin Lesions of Fibrocytic and Fibrohistiocytic Differentiation: A New Concept and Classification. In: Cerio, R. (eds) Dermatopathology. Current Topics in Pathology, vol 94. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59552-3_7

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-59552-3_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-64024-7

  • Online ISBN: 978-3-642-59552-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics