Summary
Studies of five cases of post-hypoxic encephalopathy in children, and of six adults recovering from aphasia following cerebral infarction, allowed us successfully to produce images depicting atypical areas of the brain compensating for the once-lost functions. A 12- or 24-channel interface was placed on the scalp to obtain periodically a near infrared (NIR) spectrogram. By statistical analysis, the functional activity of the brain was then demonstrated through cinematographic topography. The localization and severity of tissue damage was reviewed by conventional MRI, and the morbidity of the incident was evaluated through the degree of the patient’s active daily life. The credibility of the resulting images were confirmed by comparison with an f-MRI image. As results: (1) the cortical functions for voluntary movement and sensory reception and cognition in children with bilateral loss of the pyramidal tracts is compensated by the frontal polar areas, the superior frontal gyrus, and the anterior portion of the longitudinal fissure. (2) It is possible for the contralateral homotopical area to compensate for the motor speech areas of the frontal lobe even in adults. (3) It is assumed that the ability to compensate for the lost function can be further enhanced through proper training. In conclusion, the brain is a highly plastic organ.
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Kogure, K. et al. (2001). Functional Plasticity of the Brain After Ischemic Injury Assessed by Near Infrared Topography. In: Maturation Phenomenon in Cerebral Ischemia IV. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59446-5_13
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DOI: https://doi.org/10.1007/978-3-642-59446-5_13
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-41107-9
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