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The Precursors of Malignant Melanoma

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Part of the Recent Results in Cancer Research book series (RECENTCANCER,volume 160)

Abstract

The precursors to melanoma are generally considered to be related to nevi of different types. Here we emphasize the dysplastic nevus, the congenital nevus, and lentigo maligna as specific lesions. The dysplastic nevus is discussed not only as a formal precursor but also as a marker of cutaneous melanoma. The clinical and histologic characteristics are outlined, as well as evidence of progression in dysplastic nevi. The congenital nevus is briefly reviewed and emphasis is placed upon clues to malignant degeneration. The concept of lentigo maligna as a precursor as distinct from an in situ phase is detailed.

Keywords

  • Cytologic Atypia
  • Melanocytic Nevus
  • Outer Root Sheath
  • Dysplastic Nevus
  • Vertical Growth Phase

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© 2002 Springer-Verlag Berlin Heidelberg

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Crowson, A.N., Magro, C.M., Sanchez-Carpintero, I., Mihm, M.C. (2002). The Precursors of Malignant Melanoma. In: Dummer, R., Nestle, F.O., Burg, G. (eds) Cancers of the Skin. Recent Results in Cancer Research, vol 160. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59410-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-59410-6_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63969-2

  • Online ISBN: 978-3-642-59410-6

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