Altersdepression

  • F. M. Reischies
Conference paper

Zusammenfassung

Das Altern verändert den Menschen sowohl in seinen biologisch-somatischen als auch seinen sozialen Bedingungen. Altersdepression ist eine Depression, die zunächst erst einmal nur durch das chronologische Alter definiert ist. Aber chronologisches Alter ist nicht dem somatischen Alter gleichzusetzen, weil die Alterungsprozesse individuell unterschiedlich ablaufen. Ist die Altersdepression eine Depression wie im jüngeren Erwachsenenalter, nur in einem gealterten Körper und einer gealterten Psyche? Nein, denn die somatischen und psychischen Veränderungen im Alter haben Auswirkungen auf die Depression. Wir werden die wichtigen Einflüsse der Alterungsprozesse auf verschiedene Bereiche der Depression darstellen.

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Literatur

  1. Borchelt M, Gilberg R, Horgas AL, Geiselmann B (1999) On the significance of morbidity an disability in old age. In: Baltes PB, Mayer KU (eds) The Berlin Aging Study: Aging from 70 to 100. Cambridge University Press, New York, pp 403–429.Google Scholar
  2. Bowlby J (1983) Verlust und Trauer. Fischer, Frankfurt.Google Scholar
  3. Bschor T., Reischies F.M., Bauer, M. (1998) Therapieresistente Depression: MRT-Befunde bei guter Response und bei Non-Response auf antidepressive Behandlung. Poster DGPPN Tagung.Google Scholar
  4. Cummings JL (1993) Frontal-subcortical circuits and human behavior. Arch Neurol 50:873–880.PubMedGoogle Scholar
  5. Drevets WC, Price JL, Simpson JR Jr, Todd RD, Reich T, Vannier M, Raichle ME (1997) Subgenual prefrontal cortex abnormalities in mood disorders. Nature 386:824–827.PubMedCrossRefGoogle Scholar
  6. Gaupp, R. (1905) Die Depressionszustande des hoheren Lebensalters.MMW 52:1531–1537Google Scholar
  7. Geiselmann, B., Bauer, M. (2000) Subthreshold depression in the elderly: Quantitative or qualitative distinction? Comprehensive Psychiatry 41 (Suppl l):32–38.Google Scholar
  8. Gotthardt U, Schweiger U, Fahrenberg J, Lauer CJ, Holsboer F, Heuser I (1995) Cortisol, ACTH, and cardiovascular response to a cognitive challenge paradigm in aging and depression. Am J Physiol 268:865–873.Google Scholar
  9. Greenwald BS, Kramer-Ginsberg E, Ranga Rama Krishnan K, Ashtari M, Aupperle PM, Patel M (1996) MRI signal hyperintensities in geriatric depression. Am J Psychiatry 153: 1212–1215.PubMedGoogle Scholar
  10. Helmchen, H., Baltes, M.M., Geiselmann, B. et al. (1999) Psychiatric illnesses in old age. In: Baltes PB, Mayer KU (eds) The Berlin Aging Study: Aging from 70 to 100. Cambridge University Press, New York, pp 167–196.Google Scholar
  11. Krishnan KRR (1993) Neuroanatomic substrates of depression in the elderly. J Geriatr Psychiatry Neurol 1:39–58.Google Scholar
  12. Lai, T., Payne, M.E., Byrum, C.E., Steffens, D.C., Krishnan, K.R. (2000) Reduction of orbital frontal cortex volume in geriatric depression. Biol Psychiatry 48:971–975.Google Scholar
  13. Linden M, Kurtz G, Baltes MM, Geiselmann B, Lang F, Reischies FM, Helmchen H (1998) Depression bei Hochbetagten — Ergebnisse der Berliner Altersstudie. Nervenarzt 69: 27–37.PubMedCrossRefGoogle Scholar
  14. Nair NP, Amin M, Holm P, Katona C, Klitgaard N, Ng Ying Kin NM, Kragh-Sorensen P, Kuhn H, Leek CA, Stage KB 1995. Moclobemide and nortriptyline in elderly depressed patients. A randomized, multicentre trial against placebo. J Affect Disord 33:1–9.PubMedCrossRefGoogle Scholar
  15. Nyth AL, Gottfries CG, Lyby K et al. (1992) A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr Scand 86:138–145.PubMedCrossRefGoogle Scholar
  16. Prince MJ, Reischies FM, Beekman ATF et al. (1999) Development of the EURO-D scale - a European Union initiative to compare symptoms of depression in 14 European centres. Brit J Psych 174:330–338.CrossRefGoogle Scholar
  17. Reischies F.M., v Spieß P., Stieglitz R.-D. (1990) The symptom pattern variation of unipolar depression during life span: A cross—sectional study. Compr Psych 31:457–464 CrossRefGoogle Scholar
  18. Reischies, F.M. (1997) Organische Ursachen von Therapieresistenz der Depression. In: Bauer M, Berghöfer A (Hrsg) Therapieresistente Depressionen. Springer, Berlin Heidelberg New York Tokyo, S 65–75.Google Scholar
  19. Reischies FM, Geiselmann B, Gessner R, Kanowski S, Wagner M, Wernicke T, Helmchen H (1997) Demenz bei Hochbetagten — Ergebnisse der Berliner Altersstudie. Nervenarzt 68: 719–729.PubMedCrossRefGoogle Scholar
  20. Reischies FM (1999) Pattern of disturbance of different ventral frontal functions in organic depression. In: McGinty JF (ed) Advancing from the ventral striatum to the extended amygdala. Annals of the New York Academy of Science, New York 877:775–780.CrossRefGoogle Scholar
  21. Reischies FM, Neu P (2000) Comorbidity of mild cognitive disorder and depression - a neuropsychological analysis. Eur Arch Psychiatry Clin Neurosci 250:186–193.PubMedCrossRefGoogle Scholar
  22. Reynolds CF III, Frank E, Dew MA, Houck PR, Miller M, Mazumdar S, Perel JM, Kupfer DJ (1999) Treatment of 70(+)-year-olds with recurrent major depression. Excellent short- term but brittle long-term response. Am J Geriatr Psychiatry 7:64–69.Google Scholar
  23. Reynolds CF III, Frank E, Kupfer DJ, Thase ME, Perel JM, Mazumdar S, Houck PR (1996) Treatment outcome in recurrent major depression: a post hoc comparison of elderly (“young old”) and midlife patients. Am J Psychiatry 153:1288–1292.PubMedGoogle Scholar
  24. Robinson RG, Travella JI (1996) Neuropsychiatry of mood disorders. In: Fogel BS, Schiffer RB, Rao SM (eds) Neuropsychiatry. Williams & Wilkins, Baltimore, pp 287–305Google Scholar
  25. Roth M, Mountjoy CQ, Amrein R (1996) Moclobemide in elderly patients with cognitive decline and depression: an international double-blind, placebo-controlled trial. Br J Psychiatry 168:149–157.PubMedCrossRefGoogle Scholar
  26. Schultz W, Dayan P, Montague PR (1997) A neural substrate of prediction and reward. Science 275:1593–1599.PubMedCrossRefGoogle Scholar
  27. Small GW, Hamilton SH, Bystritsky A, Meyers BS, Nemeroff CB (1995) Clinical response predictors in a double-blind, placebo-controlled trial of fluoxetine for geriatric major depression. Fluoxetine Collaborative Study Group. Int Psychogeriatr 7 (Suppl):41–53.Google Scholar
  28. Smith J, Baltes PB (1999) Trends and profiles of psychological functioning in very old age. In: Baltes PB, Mayer KU (eds) The Berlin Aging Study. Cambridge University Press, pp 197–226.Google Scholar
  29. Steinacher B, Reischies FM, Stieglitz R-D (1998) Verlaufserfassung der Befindlichkeit bei de¬pressiven Patienten. Nervenarzt 69:586–591.PubMedCrossRefGoogle Scholar
  30. Wernicke TF, Reischies FM (1994) Prevalence of dementia in old age - clinical diagnoses in subjects aged 95 years and over. Neurology 44:250–253.PubMedGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 2002

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  • F. M. Reischies

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