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Thrombophilic Risk Parameters in Juvenile »Idiopathic« Stroke Patients

  • Conference paper
31st Hemophilia Symposium Hamburg 2000

Abstract

Within the last decade, various genetic defects of proteins regulating blood coagulation, particularly those affecting the physiological anticoagulant systems, have been well established as risk factors of cerebrovascular disease in adults [8;22;23]. Besides the high thrombotic risk reported in patients with homozygous FV:R506Q mutation, homozygous protein C deficiency, homozygous protein S deficiency and homozygous homocysteinuria due to cystathionine-ß-synthase (CBS) deficiency, a high risk of early thrombotic onset is observed in patients with heterozygous anti-thrombin deficiency, heterozygous protein C deficiency of the so-called dominant type, and heterozygous protein S deficiency [18;29;40].

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© 2002 Springer-Verlag Berlin Heidelberg

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Krause, M., Ehrenforth, S., Aygören-Pürsün, E., Ludwig, G., Scharrer, I. (2002). Thrombophilic Risk Parameters in Juvenile »Idiopathic« Stroke Patients. In: Scharrer, I., Schramm, W. (eds) 31st Hemophilia Symposium Hamburg 2000. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59383-3_36

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  • DOI: https://doi.org/10.1007/978-3-642-59383-3_36

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42131-3

  • Online ISBN: 978-3-642-59383-3

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