Hereditary Antithrombin Deficiency — Results of a Family Study
Venous thrombosis or thromboembolism in younger people and especially in children or adolescents is in the majority of cases related to one or more inherited defects of naturally occurring antithrombotic proteins.
KeywordsAnticardiolipin Antibody Antithrombin Activity Antithrombin Deficiency Factor Versus Gene Venous Thromboembolic Complication
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- 1.Andrew M, David M, Adams M, Ali K, Anderson R, Barnard D, Bernstein M, Brisson L, Cairney B, De Sai D, Grant R, Israels S, Jardine L, Luke B, Masciotte P, Silva M (1994). Venous thromboembolic complications (VTE) in children: first analyses of the Canadian registry of VTE. Blood 83: 1251–1257PubMedGoogle Scholar
- 5.Halbmayer W M, Mannhalter C, Feichtinger C, Rubi K, Fischer M (1992). The prevalence of factor XII deficiency in 103 orally anticoagulated outpatients suffering from recurrent venous and or arterial thromboembolism. Thromb Haemostas 68: 285–290Google Scholar
- 14.de Stefano V, Leone G, Mastrangelo S, Tripodi A, Rodeghiro F, Castaman G, Barbui T, Finazzi G, Bizzi B, Mannucci P M (1994). Clinical manifestations and management of inherited thrombophilia• retrospective analysis and follow-up after diagnosis of 238 patients with congenital deficiency of antithrombin III, protein C, protein S. Thrombos Haemostas 72: 352–358Google Scholar
- 15.Taisuke K, Takashi 0, Koichi 0, Mika K, Kazuya S, Naotaka H, Yoshiyuki N (1998). A common genetic polymorphism (46 C to T substitution) in the 5’-untranslated region of the coagulation factor XII gene is associated with low translation efficiency and decrease in plasma factor XII level. Blood 91: 2010–2014Google Scholar