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In Vitro Sensitivity to Chemotherapy-Induced Apoptosis in CD2+ve and CD2-ve Childhood T-All

  • Conference paper
Acute Leukemias IX

Part of the book series: Haematology and Blood Transfusion Hämatologie und Bluttransfusion ((HAEMATOLOGY,volume 41))

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Abstract

T-lineage acute lymphoblastic leukemia (T- ALL) account for approximately 15% of all childhood acute leukemias and has been reported to have a worse prognosis than B- lineage ALL (Reiter et al., 1994; Uckun et al., 1998). However, the reasons for the increased drug resistance of T-ALLcells are not clear yet (Uckun et al., 1998).

This work was supported by grants of the “Deutsché Jose Carreras Leukämie Stiftung” (JCLS 1998/NAT-3 to C.W.), the “Deutsche Leukämie-Forschungshilfe” (DLFH-98.04 to V.R.), and the “Monika-Kutzner-Stif- tung”.

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Authors and Affiliations

  1. Dept. of Hermatology, Oncology, and Tumor Immunology, Robert-Rössle-Clinic, Chartité, Humboldt-University of Berlin, Germany

    C. Wuchter, V. Ruppert, A. Mrozek, P. T. Daniel, B. Dörken, W.-D. Ludwig & L. Karawajew

  2. InViTek GmbH, Berlin-Buch, Germany

    T. Hillebrand

Authors
  1. C. Wuchter
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  2. V. Ruppert
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  3. A. Mrozek
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  4. T. Hillebrand
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  5. P. T. Daniel
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  6. B. Dörken
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  7. W.-D. Ludwig
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  8. L. Karawajew
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Editor information

Editors and Affiliations

  1. Klinikum Grofihadern Med. Klinik III, Ludwig-Maximilians-Universität, Marchioninistr. 15, 81377, München, Germany

    Wolfgang Hiddemann , Torsten Haferlach  & Michael Unterhalt ,  & 

  2. Department of Internal Medicine A, University of Münster, Albert-Schweitzer-Str. 33, 48149, Münster, Germany

    Thomas Büchner

  3. Department of Pediatric Hematology/Oncologic, University of Münster, Albert-Schweitzer-Str. 33, 48149, Münster, Germany

    Jörg Ritter

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© 2003 Springer-Verlag Berlin Heidelberg

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Wuchter, C. et al. (2003). In Vitro Sensitivity to Chemotherapy-Induced Apoptosis in CD2+ve and CD2-ve Childhood T-All. In: Hiddemann, W., Haferlach, T., Unterhalt, M., Büchner, T., Ritter, J. (eds) Acute Leukemias IX. Haematology and Blood Transfusion Hämatologie und Bluttransfusion, vol 41. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-59358-1_40

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  • DOI: https://doi.org/10.1007/978-3-642-59358-1_40

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63949-4

  • Online ISBN: 978-3-642-59358-1

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