New Developmental Agents and Directions in the Treatment of Acute Myelogenous Leukemia

  • B. D. Cheson
Conference paper
Part of the Haematology and Blood Transfusion Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 41)


The prognosis for patients with acute myelogenous leukemia (AML) has not improved substantially in more than a decade. Regimens based on an anthracycline (e.g. daunorubicin) and cytarabine, induce complete remissions in 60-80% of patients under the age of 55 years with a projected long-term disease free survival of 25-50%; the figures for older patients are 25-30% and <15%, respectively. Higher doses with stem cell support have not been associated with major benefit [9]. Clearly new approaches are needed to improve the outlook for these patients


Acute Myeloid Leukemia Acute Leukemia Acute Promyelocytic Leukemia Sodium Butyrate Boronic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 2003

Authors and Affiliations

  • B. D. Cheson
    • 1
  1. 1.National Cancer Institute, Executive Plaza North - Rm 741BethesdaUSA

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