Electrophoresis in the Field of Forensic Science
One of the main topics in the field of forensic science is the typing of biological materials for the purpose of identification of individuals, specifically for paternity and forensic testing. This genetic characterization of biological materials is being performed increasingly at the DNA level. At present, polymorphic loci whose alleles are the result of the variable number of tandem repeats (VNTRs) (Nakamura et al. 1987) or short tandem repeats (STRs) (Edwards et al. 1991) are the most informative markers for individualizing biological material. The VNTR/STR polymorphism is based on differences in the number of core repeat units contained within alleles carried among individuals. While different protocols are performed in the analysis of these polymorphic regions, the separation of these products usually is performed by electrophoresis.
KeywordsShort Tandem Repeat Short Tandem Repeat Locus Material Safety Data Sheet Material Safety Data Sheet Allelic Ladder
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