Antisense Properties of Peptide Nucleic Acid

  • P. E. Nielsen
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 131)


The hybridization properties of peptide nucleic acid (PNA) combined with its ease of synthesis and high chemical and biological stability rapidly made this molecule a very attractive lead compound for the development of antisense gene therapeutic drugs.


Peptide Nucleic Acid Strand Displacement Adenine Cytosine Sequence Discrimination Peptide Nucleic Acid Oligomer 
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© Springer-Verlag Berlin Heidelberg 1998

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  • P. E. Nielsen

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