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Liver Malignancies pp 275–292Cite as

Percutaneous Ethanol Injection of Hepatocellular Carcinoma and Borderline Lesions

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Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

Abstract

Hepatocellular carcinoma (HCC) is one of the most common neoplasms worldwide and occurs in association with cirrhosis in over 90% of patients (Colombo et al. 1991). Presently, many patients with cirrhosis undergo screening procedures that permit the early detection of HCC. As a result of widespread screening programs, the detection of HCC while it is small and unifocal has increased significantly (Bartolozzi et al. 1995b; Lencioni et al. 1996). Unfortunately, many patients with HCC are not suitable candidates for hepatic resection. Surgery is often precluded because of hepatic dysfunction secondary to underlying cirrhosis. These patients have little functional reserve and would be at high risk for postoperative hepatic failure. Also, because of the associated cirrhosis, these patients are at high risk for the development of future tumors (Bartolozzi and Lencioni 1996; Colombo et al. 1991; Trevisani et al. 1993). That is, the initial lesion may be the prelude to other lesions. The metachronous nature of HCC in patients with cirrhosis must be considered when treatment options are weighted. Because of the significant underlying hepatic disease, treatment methods that result in minimal damage to uninvolved hepatic parenchyma are best for the majority of patients with HCC (Lin et al. 1997; Imamura et al. 1998; De Sanctis et al. 1998).

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  1. Division of Diagnostic and Interventional Radiology, Department of Oncology, University of Pisa, Via Roma 67, I-56125, Pisa, Italy

    R. Lencioni MD, D. Cioni MD, A. Paolicchi MD, M. Moretti MD, A. Cicorelli MD & C. Bartolozzi MD (Professor and Chairman)

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  1. Division of Diagnostic and Interventional Radiology, Department of Oncology, University of Pisa, Via Roma 67, I-56125, Pisa, Italy

    C. Bartolozzi MD (Professor and Chairman) & R. Lencioni MD (Professor and Chairman) & 

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Lencioni, R., Cioni, D., Paolicchi, A., Moretti, M., Cicorelli, A., Bartolozzi, C. (1999). Percutaneous Ethanol Injection of Hepatocellular Carcinoma and Borderline Lesions. In: Bartolozzi, C., Lencioni, R. (eds) Liver Malignancies. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58641-5_18

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