Abstract
Acute rupture of an atherosclerotic plaque exposes thrombogenic structures of the vascular wall. Platelets in the circulating blood adhere to the injured vascular wall, are activated, and release thrombogenic signals. Thereby more and more platelets are recruited into the thrombus. In the most serious cases, this rapidly growing thrombus occludes the blood vessel and initiates a sequence of events resulting in irreversible injury of the tissue.
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© 1990 Springer-Verlag Berlin Heidelberg
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Müller, T.H., Eisert, W.G. (1990). Human Endothelial Cells Modulate Thrombus Formation in an In Vitro Model of Platelet-Vessel Wall Interactions. In: Kessler, C. (eds) Platelets and Atherosclerosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58225-7_7
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DOI: https://doi.org/10.1007/978-3-642-58225-7_7
Publisher Name: Springer, Berlin, Heidelberg
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Online ISBN: 978-3-642-58225-7
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